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Jelleine is a family ofpeptides, isolated from theroyal jelly ofApis mellifera iberiensis, asubspecies of thehoney bee. This new family has the potential to be used in the development of new drugs.[1]
Jelleines were first isolated in 2004 by the research group of Professor Mario Sergio Palma atSão Paulo State University, Brazil. First, he collected royal jelly from a group of honey bee larvae and purified the results by reverse phase,high-performance liquid chromatography. This purified royal jelly showed antimicrobial activity against different bacteria.[2] So far, four peptides have been found in this family, each one containing thecarboxamide C-terminal.
Jelleine exhibits antimicrobial activity againstS. epidermidis.[3]