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Jejunum

From Wikipedia, the free encyclopedia
Part of the small intestine
Not to be confused withduodenum.
Jejunum
Small intestine
Superior and inferior duodenal fossæ.
Details
Pronunciation/ɪˈnəm/jij-OO-nəm[2][3]
Precursorlaude
Part ofSmall intestine
SystemDigestive system
ArteryJejunal arteries
VeinJejunal veins
NerveCeliac ganglia,vagus[1]
Identifiers
Latinjejunum
MeSHD007583
TA98A05.6.03.001
TA22958
FMA7207
Anatomical terminology
Major parts of the
Gastrointestinal tract

Thejejunum is the second part of thesmall intestine inhumans and mosthigher vertebrates, includingmammals,reptiles, andbirds. Its lining is specialized for the absorption byenterocytes of small nutrientmolecules which have been previously digested byenzymes in theduodenum.

The jejunum lies between theduodenum and theileum and is considered to start at thesuspensory muscle of the duodenum, a location called theduodenojejunal flexure.[4] The division between the jejunum and ileum is not anatomically distinct.[5] In adulthumans, the small intestine is usually 6–7 m (20–23 ft) long (post mortem), about two-fifths of which (about 2.5 m (8.2 ft)) is the jejunum.[4]

Structure

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See also:Small intestine

The interior surface of the jejunum—which is exposed to ingested food—is covered in finger–like projections of mucosa, calledvilli, which increase the surface area of tissue available to absorb nutrients from ingested foodstuffs. The epithelial cells which line these villi havemicrovilli. The transport of nutrients across epithelial cells through the jejunum and ileum includes thepassive transport of sugarfructose and theactive transport ofamino acids, smallpeptides,vitamins, and mostglucose. The villi in the jejunum are much longer than in the duodenum or ileum.

ThepH in the jejunum is usually between 7 and 8 (neutral or slightlyalkaline).

The jejunum and the ileum are suspended bymesentery which gives the bowel great mobility within theabdomen. It also contains circular and longitudinalsmooth muscle which helps to move food along by a process known asperistalsis.

Histology

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The jejunum contains very fewBrunner's glands (found in the duodenum) orPeyer's patches (found in the ileum). However, there are a few jejunallymph nodes suspended in its mesentery. The jejunum has many largecircular folds in itssubmucosa calledplicae circulares that increase the surface area for nutrient absorption. The plicae circulares are best developed in the jejunum.

There is no line of demarcation between the jejunum and the ileum. However, there are subtlehistological differences:

  • The jejunum has less fat inside its mesentery than the ileum.
  • The jejunum is typically of larger diameter than the ileum.
  • The villi of the jejunum look like long, finger-like projections, and are a histologically identifiable structure.
  • While the length of the entire intestinal tract containslymphoid tissue, only the ileum has abundantPeyer's patches, which are unencapsulatedlymphoid nodules that contain large numbers oflymphocytes and immune cells, likemicrofold cells.

Function

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The lining of the jejunum is specialized for the absorption byenterocytes of small nutrient particles which have been previously digested byenzymes in theduodenum. Once absorbed, nutrients (with the exception of fat, which goes to the lymph) pass from the enterocytes into theenterohepatic circulation and enter theliver via the hepatic portal vein, where the blood is processed.[6]

Other animals

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Infish, the divisions of the small intestine are not as clear and the termsmiddle intestine ormid-gut may be used instead of jejunum.[7]

History

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Etymology

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Jejunum is derived from theLatin wordjējūnus (iēiūnus), meaning "fasting." It was so called because this part of thesmall intestine was frequently found to be void of food followingdeath,[8] due to its intensiveperistaltic activity relative to theduodenum andileum.

TheEarly Modern English adjectivejejune is derived from the same root.[9]

References

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  1. ^Nosek, Thomas M."Section 6/6ch2/s6ch2_30".Essentials of Human Physiology. Archived fromthe original on 2016-03-24.
  2. ^OED 2nd edition, 1989.
  3. ^Entry "jejunum" inMerriam-Webster Online Dictionary.
  4. ^abDrake, Richard L.; Vogl, Wayne; Tibbitts, Adam W. M. Mitchell; illustrations by Richard; Richardson, Paul (2005).Gray's anatomy for students. Philadelphia: Elsevier/Churchill Livingstone. pp. 273–275.ISBN 978-0-8089-2306-0.
  5. ^Deakin, Barbara Young; et al. (2006).Wheater's functional histology : a text and colour atlas (5th ed.). Churchill Livingstone/Elsevier. p. 263.ISBN 978-0-443-068-508.
  6. ^CRANE, RK (Oct 1960). "Intestinal absorption of sugars".Physiological Reviews.40 (4):789–825.doi:10.1152/physrev.1960.40.4.789.PMID 13696269.
  7. ^Guillaume, Jean; Praxis Publishing; Sadasivam Kaushik; Pierre Bergot; Robert Metailler (2001).Nutrition and Feeding of Fish and Crustaceans. Springer. p. 31.ISBN 9781852332419. Retrieved2009-01-09.
  8. ^Harper, Douglas."jejunum".Etymology Online. Retrieved15 November 2014.
  9. ^"Oxford English Dictionary: jejune, adj".

External links

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Anatomy of thegastrointestinal tract, excluding themouth
Upper
Pharynx
Esophagus
Stomach
Lower
Small intestine
Microanatomy
Duodenum
Jejunum
  • No substructures
Ileum
Large intestine
Cecum
Colon
Rectum
Anal canal
Wall
National
Other
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