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| Formula | C26H26N2O3 |
| Molar mass | 414.505 g·mol−1 |
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JWH-198 is a drug from theaminoalkylindole andnaphthoylindole families which acts as acannabinoid receptoragonist. It was invented by the pharmaceutical company Sanofi-Winthrop in the early 1990s. JWH-198 has abinding affinity at the CB1 receptor of 10 nM, binding around four times more tightly than the parent compoundJWH-200, which has no substitution on the naphthoyl ring.[1] It has been used mainly inmolecular modelling of the cannabinoid receptors.[2][3]
In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-198 areSchedule I Controlled Substances.[4]
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