JWH-057

Legal status
Legal status	DE: unscheduled[1]
Identifiers
IUPAC name (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-Dibenzo[b,d]pyran
CAS Number	105823-04-9 Y
ChemSpider	114395
UNII	8I28LF0B2D
CompTox Dashboard(EPA)	DTXSID90147357
Chemical and physical data
Formula	C25H38O
Molar mass	354.578 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCCC(C)(C)C1=CC2=C(C=C1)[C@@H]3CC(=CC[C@H]3C(O2)(C)C)C
InChI InChI=1S/C25H38O/c1-7-8-9-10-15-24(3,4)19-12-13-20-21-16-18(2)11-14-22(21)25(5,6)26-23(20)17-19/h11-13,17,21-22H,7-10,14-16H2,1-6H3/t21-,22+/m0/s1 Key:JEEFMLVJZKFOFV-FCHUYYIVSA-N

JWH-057, also known as deoxy-Δ8-THC-DMH, is a selectivecannabinoid ligand, with a binding affinity of K_i = 2.9 ± 1.6 nM for theCB₂ subtype, and K_i = 23 ± 7 nM forCB₁.^[2]

• JWH-015
• JWH-018
• JWH-019
• JWH-073

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