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J. Michael Bishop

From Wikipedia, the free encyclopedia
American immunologist and microbiologist (born 1936)
Not to be confused withMichael J. Bishop.
J. Michael Bishop
Portrait of Bishop
Born
John Michael Bishop

(1936-02-22)February 22, 1936 (age 89)
EducationGettysburg College (Bachelors)
Harvard University (MD)
Known forOncogeneVirus
Awards
Scientific career
FieldsVirology
Institutions
Websiteprofiles.ucsf.edu/j.michael.bishop

John Michael Bishop (born February 22, 1936) is an Americanimmunologist andmicrobiologist who shared the 1989Nobel Prize in Physiology or Medicine withHarold E. Varmus.[1] He serves as an active faculty member at theUniversity of California, San Francisco (UCSF), where he also served as chancellor from 1998 to 2009.[2][3][4][5][6]

Education and early life

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Bishop was born inYork, Pennsylvania. He attendedGettysburg College as an undergraduate, where he was a brother of the Theta-Pi Zeta chapter ofLambda Chi Alpha fraternity. He later attendedHarvard University Medical School, where he earned anMD in 1962.[7]

Career

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Bishop began his career working for theNational Institute of Allergy and Infectious Diseases, a part of theNational Institutes of Health. He then spent a year working for theHeinrich Pette Institute inHamburg,Germany before joining the faculty of theUniversity of California, San Francisco in 1968.[3] Bishop has remained on the school's faculty since 1968, and was chancellor of the university from 1998 to 2009.[5] He is director of the Bishop Lab.[8]

He became the eighth chancellor of UCSF in 1998. He oversaw one of UCSF's major transition and growth periods, including the expanding Mission Bay development and philanthropic support recruitment. During his tenure, he unveiled the first comprehensive, campus-wide, strategic plan to promote diversity and foster a supportive work environment. During this time, UCSF also adopted a new mission:advancing health worldwide™.[9]

Research

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Much of this work was conducted jointly with Harold Varmus in a notably long scientific partnership. Their best-known accomplishment[10] was the identification of a cellular gene (c-src) that gave rise to the v-src oncogene of Rous Sarcoma Virus, a cancer-causing virus first isolated from a chicken sarcoma byPeyton Rous in 1910. Their discovery triggered the identification of many other cellular proto-oncogenes—progenitors of viral oncogenes and targets for mutations that drive human cancers.

Awards and honors

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Bishop is best known for his Nobel-winning work onretroviraloncogenes. Working withHarold E. Varmus in the 1980s, he discovered the first human oncogene,c-Src. Their findings allowed the understanding of how malignanttumors are formed from changes to the normalgenes of acell. These changes can be produced by viruses, by radiation, or by exposure to some chemicals.[4][11][12][13]

Bishop is a member of theNational Academy of Sciences,[14] theAmerican Academy of Arts and Sciences,[15] and theAmerican Philosophical Society.[16]

Bishop is also a recipient ofNational Medal of Science in 2003.[6] That same year, his book "How to win the Nobel Prize: An Unexpected Life in Science" was published. He was electedForeign Member of the Royal Society (ForMemRS) in 2008.[17]In 2020, Bishop received from theUC Berkeley Academic Senate theClark Kerr Award for distinguished leadership in higher education.[18]

Archival collections

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The University of California, San Francisco Archives and Special Collections houses a collection of J. Michael Bishop papers, including his laboratory research notebooks, writings, photographs, and other material.[19]

References

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  1. ^NCI Visuals Online: Image Details. Visualsonline.cancer.gov. Retrieved on 2013-11-24.
  2. ^J. Michael Bishop on Nobelprize.orgEdit this at Wikidata, accessed 12 October 2020
  3. ^abAutobiography on UCSF WebsiteArchived August 10, 2014, at theWayback Machine
  4. ^abNobel Prize press release
  5. ^ab"Susan Desmond-Hellmann named UC San Francisco chancellor". Archived fromthe original on 2010-06-10. Retrieved2010-02-18.
  6. ^abNational Medal of Science details
  7. ^Shampo, Marc A.; Kyle, Robert A. (2002)."J. Michael Bishop—Nobel Laureate in Medicine or Physiology".Mayo Clinic Proceedings.77 (12): 1312.doi:10.4065/77.12.1312.PMID 12479518.
  8. ^Bishop Lab. Hooper.ucsf.edu. Retrieved on 2013-11-24.Archived December 2, 2013, at theWayback Machine
  9. ^"John Michael Bishop - Biography - A History of UCSF".history.library.ucsf.edu.
  10. ^Stehelin, D.; Varmus, H. E.; Bishop, J. M.; Vogt, P. K. (1976-03-11). "DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA".Nature.260 (5547):170–173.Bibcode:1976Natur.260..170S.doi:10.1038/260170a0.PMID 176594.S2CID 4178400.
  11. ^"Michael Bishop archival collection at UCSF". Archived fromthe original on 2015-10-22. Retrieved2015-05-14.
  12. ^J. Michael Bishop at AccesExcellence.orgArchived 2009-07-15 at theWayback Machine
  13. ^J. Michael Bishop's lecture: "Cancer: The rise of the genetic paradigm"
  14. ^"J. Michael Bishop".www.nasonline.org. Retrieved2021-12-20.
  15. ^"John Michael Bishop".American Academy of Arts & Sciences. Retrieved2021-12-20.
  16. ^"APS Member History".search.amphilsoc.org. Retrieved2021-12-20.
  17. ^"Professor J Michael Bishop ForMemRS". London:Royal Society. Archived fromthe original on 2015-10-21.
  18. ^"History of the Clark Kerr Award | Academic Senate".academic-senate.berkeley.edu. Retrieved2021-02-13.
  19. ^Calisphere J. Michael Bishop Collection:https://calisphere.org/collections/26395/

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