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Isothipendyl

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Chemical compound

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Pharmaceutical compound
Isothipendyl
Skeletal formula
Ball-and-stick model of isothipendyl
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-amine
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
ECHA InfoCard100.006.890Edit this at Wikidata
Chemical and physical data
FormulaC16H19N3S
Molar mass285.41 g·mol−1
3D model (JSmol)
  • n2c1N(c3c(Sc1ccc2)cccc3)CC(N(C)C)C
  • InChI=1S/C16H19N3S/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19/h4-10,12H,11H2,1-3H3 checkY
  • Key:OQJBSDFFQWMKBQ-UHFFFAOYSA-N checkY
  (verify)

Isothipendyl is a 1st generationH1 antagonist (antihistamine) andanticholinergic used as anantipruritic.[1] In the 2020s, at least, it is rarely used in the first line relief of allergies due to the anticholinergic side effect ofsomnolence but does have some limited use throughtopical application in the relief ofinsect bites and relateditching (pruritus).[citation needed]

See also

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References

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  1. ^Bibas N, Sartor V, Bulai Livideanu C, Bagheri H, Nougué J, Giordano-Labadie F, et al. (2012). "Contact photoallergy to isothipendyl chlorhydrate".Dermatology.224 (4):289–291.doi:10.1159/000338024.PMID 22677929.S2CID 27580642.
Benzimidazoles(*)
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Fortopical use
Antihistamines fortopical use
Anesthetics for topical use
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H1
Agonists
Antagonists
H2
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H3
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H4
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Antidepressants
(Tricyclic antidepressants(TCAs))
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