 | This articleneeds additional citations forverification. Please helpimprove this article byadding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "Irreversible agonist" – news ·newspapers ·books ·scholar ·JSTOR(January 2013) (Learn how and when to remove this message) |
Anirreversible agonist is a type ofagonist that binds permanently to a receptor in such a manner that the receptor is permanently activated. It is distinct from a mere (reversible) agonist in that the association of an agonist to a receptor is reversible, whereas the binding of an irreversible agonist to a receptor is, at least in theory, irreversible. Oxymorphazone is an example of an irreversible agonist.[1] In practice, the distinction may be more a matter of degree, in which the binding affinity of an irreversible agonist is some orders of magnitude greater than that of an agonist.
 | Thispharmacology-related article is astub. You can help Wikipedia byadding missing information. |