Iroquois homeobox factors are a family ofhomeodomaintranscription factors that play a role in manydevelopmental processes.[1][2] The loci were named for the flies carrying mutations in one of these genes, which are devoid of all bristles in the lateral part of the notum, leaving only a median stripe of bristles, similar to theIroquois tribes which shaved all but amedial stripe of hairs on the head.[3]
Human genes that encode Iroquois homeobox factors include:[2]