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Ionic partition diagram

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Similar toPourbaix diagrams for the speciation ofredox species as a function of the redox potential and thepH,ionic partition diagrams indicate in which phase an acid or a base is predominantly present in abiphasic system as a function of theGalvani potential difference between the two phases and the pH of the aqueous solution. One of the functions of these diagrams is to reveal drug transport across biological membranes.[1]

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References

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  1. ^Reymond, Frédéric; et al. (1999). "Ionic partition diagrams of ionisable drugs: pH-lipophilicity profiles, transfer mechanisms and charge effects on solvation".Journal of Electroanalytical Chemistry.462 (2):235–250.doi:10.1016/S0022-0728(98)00418-5.


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