| Interposed nucleus | |
|---|---|
| Details | |
| Identifiers | |
| Latin | nucleus interpositus anterior, nucleus interpositus posterior |
| NeuroLex ID | nlx_anat_20081242 |
| Anatomical terms of neuroanatomy | |
Theinterposed nucleus is the combined pairedglobose andemboliform nuclei, (deep cerebellar nuclei) on either side of thecerebellum.[1][2] It is located in theroof of the fourth ventricle, lateral to thefastigial nucleus. The emboliform nucleus is theanterior interposed nucleus, and the globose nucleus is theposterior interposed nucleus.[3]
The interposed nucleus is responsible for coordinating agonist/antagonist muscle pairs, and therefore a lesion in this area causestremor.
The interposed nucleus is located in the paravermis of the cerebellum.[citation needed]
The interposed nucleus is smaller than the dentate but larger than the fastigial nucleus.[citation needed]
The interposed nuclei receives Purkine cell terminal afferents from the paravermal cortex of thespinocerebellum, as well as collaterals of cerebellar afferents from therestiform body andventral spinocerebellar tract.[2]
It receives input from the ipsilateralposterior external arcuate fibers (cuneocerebellar tract) and thedorsal spinocerebellar tract, which originate in theaccessory cuneate nucleus and theposterior thoracic nucleus, respectively.[citation needed]
Afferents from the interposed nuclei leave the cerebellum throughsuperior cerebellar peduncle. They project to:[2]
The rubrospinal and lateral corticospinal tracts are subsequently involved in control of the distal musculature of the extremities.
The interposed nucleus modulates muscle stretch reflexes of proximal limb muscles, and is also required in delayedPavlovian conditioning.[4]
 | Thisneuroanatomy article is astub. You can help Wikipedia byexpanding it. |