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Interleukin-18 receptor

From Wikipedia, the free encyclopedia
interleukin 18 receptor 1
Identifiers
SymbolIL18R1
Alt. symbolsIL1RRP, IL-1Rrp, CD218a
NCBI gene8809
HGNC5988
OMIM604494
RefSeqNM_003855
UniProtQ13478
Other data
LocusChr. 2q12
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 18 receptor accessory protein
Identifiers
SymbolIL18RAP
Alt. symbolsAcPL, CD218b
NCBI gene8807
HGNC5989
OMIM604509
RefSeqNM_003853
UniProtO95256
Other data
LocusChr. 2p24.3-24.1
Search for
StructuresSwiss-model
DomainsInterPro

Theinterleukin-18 receptor (IL-18R) is aninterleukin receptor of theimmunoglobulin superfamily.[1][2]

Endometrial IL-18 receptor mRNA and the ratio ofIL-18 binding protein to interleukin 18 are significantly increased inadenomyosis patients in comparison to normal people, indicating a role in its pathogenesis.[3]

References

[edit]
  1. ^Sergi B, Penttila I (2004). "Interleukin 18 receptor".J. Biol. Regul. Homeost. Agents.18 (1):55–61.PMID 15323361.
  2. ^Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T (2003)."IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction".J. Immunol.170 (11):5571–7.doi:10.4049/jimmunol.170.11.5571.PMID 12759435.
  3. ^Huang, H.; Yu, H.; Chan, S.; Lee, C.; Wang, H.; Soong, Y. (2010)."Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients".Fertility and Sterility.94 (1):33–39.doi:10.1016/j.fertnstert.2009.01.132.PMID 19394601.

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