Integrin alpha-1 alsoCD49a is anintegrin alpha subunit encoded in humans by the geneITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a can bind a number of ligands including collagen IV, collagen I, and others.[5]
CD49a has been implicated as a marker of tissue resident memory T cells, where it may be coexpressed with other markers CD103 and CD69.[6] It has been shown to affect the motility of T cells.[7]
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