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Indenolol

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Indenolol
Names

IUPAC name 1-(1H-Inden-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Identifiers
CAS Number	60607-68-3^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL153585
ChemSpider	64962
DrugBank	DB08952^N
EC Number	262-323-5
KEGG	D08078
PubChem CID	71955
UNII	3MZM7RWW00^Y
CompTox Dashboard(EPA)	DTXSID70866817
InChI InChI=1S/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3 Key: MPGBPFMOOXKQRX-UHFFFAOYSA-N InChI=1/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3 Key: MPGBPFMOOXKQRX-UHFFFAOYAY
SMILES CC(C)NCC(COC1=CC=CC2=C1C=CC2)O
Properties
Chemical formula	C₁₅H₂₁NO₂
Molar mass	247.338 g·mol⁻¹
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chemical compound

Indenolol is abeta-adrenergic blocker^[1] for the treatment ofhypertension (high blood pressure). It was investigated in the 1980s,^[2] but is not known to be marketed as of 2021^[update].^[3] It is a derivative of a phenolic 4-indenol.

References

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^Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). "Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC".Talanta.78 (2):458–63.doi:10.1016/j.talanta.2008.11.043.PMID 19203609.
^Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). "Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol".The Journal of Clinical Pharmacology.25 (5):328–336.doi:10.1002/j.1552-4604.1985.tb02850.x.PMID 4031109.S2CID 22844379.
^DrugBank DB08952. Accessed 2021-03-18.