Early placenta insulin-like peptide is aprotein that in humans is encoded by theINSL4gene.[3][4][5]
INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the earlyplacentalcytotrophoblast andsyncytiotrophoblast.[5]
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Chassin D, Laurent A, Janneau JL, Berger R, Bellet D (Aug 1996). "Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta".Genomics.29 (2):465–70.doi:10.1006/geno.1995.9980.PMID8666396.
^Veitia R, Laurent A, Quintana-Murci L, Ottolenghi C, Fellous M, Vidaud M, McElreavey K (Oct 1998). "The INSL4 gene maps close to WI-5527 at 9p24.1→p23.3 clustered with two relaxin genes and outside the critical region for the monosomy 9p syndrome".Cytogenet Cell Genet.81 (3–4):275–7.doi:10.1159/000015045.PMID9730618.S2CID46801238.
