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| Trade names | Viadril, Predion, Presuren |
| Other names | 21-Hydroxy-5β-pregnane-3,20-dione |
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| Formula | C21H32O3 |
| Molar mass | 332.484 g·mol−1 |
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Hydroxydione, ashydroxydione sodium succinate (INNTooltip International Nonproprietary Name,USANTooltip United States Adopted Name,BANTooltip British Approved Name) (brand namesViadril,Predion, andPresuren),[2][3][4] also known as21-Hydroxy-5β-pregnane-3,20-dione, is aneuroactive steroid which was formerly used as ageneral anesthetic, but was discontinued due to incidence ofthrombophlebitis in patients.[5] It was introduced in 1957,[4] and was the first neuroactive steroid general anesthetic to be introduced for clinical use, an event which was shortly preceded by the observation in 1954 of thesedative properties ofprogesterone in mice.[6]
Related compounds includealfadolone,alfaxolone,dihydrodeoxycorticosterone,ganaxolone,minaxolone,pregnanolone, andrenanolone.
