Hiroaki Suga | |
|---|---|
| Born | 菅 裕明 (1963-02-21)February 21, 1963 (age 62) Okayama, Japan |
| Education | |
| Known for | RNA-basedcatalysis |
| Awards |
|
| Scientific career | |
| Fields | Chemistry |
| Institutions | |
| Thesis | Catalytic antibodies elicited via homologous and heterologous immunization (1994) |
| Doctoral advisor | Satoru Masamune [jp] |
Hiroaki Suga (菅 裕明, born February 21, 1963) is a Japanese biochemist and businessman. He is best known for his work on artificialribozymes (flexizymes) and their application inmRNA display (RaPID, random nonstandard peptide integrated discovery).[1][2]
Suga was awarded the 2023Wolf Prize in Chemistry, jointly withChuan He andJeffery W. Kelly, "for pioneering discoveries that illuminate the functions and pathological dysfunctions ofRNA andproteins and for creating strategies to harness the capabilities of these biopolymers in new ways to ameliorate human diseases."[1]
Suga graduated fromOkayama University (BSc, MSc) in engineering,[1][3] and studied atUniversity of Lausanne, where he worked withManfred Schlosser [de].[3]
Suga completed his Ph.D. in chemistry atMassachusetts Institute of Technology in 1994 withSatoru Masamune [jp],[3] working on catalyticantibodies[4]
After graduating fromMIT with a Ph.D., Suga was apostdoctoral researcher at theJack W. Szostak lab ofHarvard Medical School before starting his independent career atUniversity at Buffalo. Since 2003 he is a faculty member at theUniversity of Tokyo.[3]
Suga is also a founder of PeptiDream Inc. Tokyo, a publicly traded biopharmaceutical start-up company responsible for discovering and developing non-standard peptide therapeutics in addition to addressing unmet medical needs as well as investigating peptide drug conjugates (PDC), peptides, and small molecule-based drugs.[5][6][7] It is traded publicly on the Tokyo First Stock Exchange Market (the market capitalization is over JY 600 billions), which has many partnerships with pharmaceutical companies in worldwide.[2][8]
Suga is chair of theeditorial board at RSC Chemical Biology[9] and associate editor atAngewandte Chemie.[2]
Suga has published over 250 scientific articles;[10] a small selection is presented here:
