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Hexafluronium bromide

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Pharmaceutical drug

Pharmaceutical compound

Hexafluronium
Clinical data

ATC code	M03AC05 (WHO)
Identifiers
IUPAC name N,N-di-9H-fluoren-9-yl-N,N,N',N'-tetramethylhexane-1,6-diaminium dibromide
CAS Number	317-52-2^N
PubChemCID	9434
DrugBank	DB00941^Y
ChemSpider	9063^Y
UNII	B64NJG83K2
KEGG	D04435^Y
CompTox Dashboard(EPA)	DTXSID6048753
ECHA InfoCard	100.005.697
Chemical and physical data
Formula	C₃₆H₄₂Br₂N₂
Molar mass	662.554 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [Br-].[Br-].c1cccc3c1c2c(cccc2)C3[N+](CCCCCC[N+](C6c4ccccc4c5ccccc56)(C)C)(C)C
InChI InChI=1S/C36H42N2.2BrH/c1-37(2,35-31-21-11-7-17-27(31)28-18-8-12-22-32(28)35)25-15-5-6-16-26-38(3,4)36-33-23-13-9-19-29(33)30-20-10-14-24-34(30)36;;/h7-14,17-24,35-36H,5-6,15-16,25-26H2,1-4H3;2*1H/q+2;;/p-2^Y Key:WDEFPRUEZRUYNW-UHFFFAOYSA-L^Y
^NY (what is this?) (verify)

Hexafluronium (orhexafluorenium) is amuscle relaxant.^[1] It acts as anicotinic acetylcholine receptor antagonist.

References

^Baraka A (August 1975)."Hexafluorenium-suxamethonium interaction in patients with normal versus atypical cholinesterase".British Journal of Anaesthesia.47 (8):885–8.doi:10.1093/bja/47.8.885.PMID 1201167.

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Skeletalmuscle relaxants (M03)

Peripherally acting
(primarilyantinicotinic,
NMJ block)

Non-depolarizing

Curare alkaloids	Alcuronium Dimethyltubocurarine Tubocurarine
4° ammonium agents	ultra-short duration:Gantacurium short duration:Rapacuronium Mivacurium Chandonium intermediate duration:Atracurium Cisatracurium Fazadinium Rocuronium Vecuronium long duration:Doxacurium Dimethyltubocurarine Pancuronium Pipecuronium Laudexium Gallamine unsorted:Hexafluronium (Hexafluorenium)

Choline derivatives:Suxamethonium (Succinylcholine)

Polyalkylene derivatives:Hexamethonium

ACh release inhibitors

Botulinum toxin

Centrally acting

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Phenprobamate Styramate Tybamate
Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam
Nonbenzodiazepines	Eszopiclone
Thienodiazepines	Etizolam
Quinazolines	Methaqualone
Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine
Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Eperisone Fenyramidol Flopropione Gabapentin GHB Inaperisone Lanperisone Mephenesin Mephenoxalone Metaxalone Methocarbamol Phenibut Pregabalin Pridinol Promoxolane Quinine Silperisone Thiocolchicoside Tizanidine Tolperisone Zoxazolamine

Directly acting

Dantrolene

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Nicotinic acetylcholine receptor modulators

nAChRsTooltip Nicotinic acetylcholine receptors

Agonists
(and PAMsTooltip positive allosteric modulators)

Antagonists
(and NAMsTooltip negative allosteric modulators)

Precursors
(andprodrugs)

See also: Receptor/signaling modulators; Muscarinic acetylcholine receptor modulators; Acetylcholine metabolism/transport modulators

Thisdrug article relating to themusculoskeletal system is astub. You can help Wikipedia byexpanding it.

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