 | |
| Names | |
|---|---|
| IUPAC name (RS)-6-Amino-2-methylheptan-2-ol | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| DrugBank | |
| ECHA InfoCard | 100.006.144 |
| EC Number |
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| MeSH | Heptaminol |
| UNII | |
| |
| |
| Properties | |
| C8H19NO | |
| Molar mass | 145.246 g·mol−1 |
| Density | 0.895 g/mL |
| Boiling point | 250 °C (482 °F; 523 K) |
| Pharmacology | |
| C01DX08 (WHO) | |
| Oral,intravenous,intramuscular | |
| Pharmacokinetics: | |
| Renal | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards | Corrosive |
| GHS labelling: | |
  | |
| Danger | |
| H314,H315,H319,H335 | |
| P260,P261,P264,P271,P280,P301+P330+P331,P302+P352,P303+P361+P353,P304+P340,P305+P351+P338,P310,P312,P321,P332+P313,P337+P313,P362,P363,P403+P233,P405,P501 | |
| Flash point | 105 °C (221 °F; 378 K) |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Heptaminol is anamino alcohol which is classified as acardiac stimulant (positive inotropic action). It also increases coronary blood flow along with mild peripheralvasoconstriction. It is sometimes used in the treatment of low blood pressure, particularlyorthostatic hypotension as it is a potent positive inotrope (improving cardiac contraction).[medical citation needed]
Heptaminol is classified by theWorld Anti-Doping Agency as adoping substance.[1] In 2008, the cyclistDmitriy Fofonov tested positive for heptaminol at theTour de France.[2] In June 2010, the swimmerFrédérick Bousquet tested positive.[3] In 2013, the cyclistSylvain Georges tested positive at theGiro d'Italia.[4] In 2014, baseball playerJoel Piniero tested positive[5] as well asSt. Louis Cardinalsminor league baseball player Yeison Medina.[6]
On March 22, 2019, Cycling South Africa reported that Ricardo Broxham has been sanctioned for an anti-doping rule violation of Articles 2.1 and 2.2 of the UCI Anti-Doping Rules after an in-competition test conducted on 18 August 2018 confirmed the presence of Heptaminol in his sample.
The UCI Anti-Doping Tribunal has imposed a period of ineligibility of 12 months for the violation, applicable as of 22 September 2018 up to and including 22 September 2019 and a disqualification of all results from the 2018 UCI Junior Track Cycling World Championships.[7]
