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Henry Harris (scientist)

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Australian professor of medicine

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Henry Harris
Born(1925-01-28)28 January 1925
Russia
Died31 October 2014(2014-10-31) (aged 89)
Alma mater
AwardsRoyal Medal
Scientific career
FieldsBiology
Institutions
ThesisNature of chemical stimuli affecting cells during tissue injury (1953)
Doctoral studentsFiona Watt[1]

Sir Henry HarrisFRS FAA (28 January 1925 – 31 October 2014)[2][3] was an Australian professor of medicine at theUniversity of Oxford who led pioneering work on cancer andhuman genetics in the 2000s.

Early life and education

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Harris was born in 1925 to a Jewish family in theSoviet Union. In 1929, his family emigrated to Australia.[2] Harris studied atSydney Boys High School from 1937 to 1941.[4] In 1941, he first readmodern languages, but was subsequently attracted to medicine through his literary interests. He studied medicine at theRoyal Prince Alfred Hospital and began a career in medical research rather than in clinical practice.

Career

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In the early 1950s, Harris moved to England to study at theSir William Dunn School of Pathology inOxford underHoward Florey. He completed hisDPhil in 1954 and settled down to a career of academic research. In 1960, he was appointed the head of the new department ofcell biology at theJohn Innes Institute, and, in 1964, he succeeded Florey as head of the Dunn School. In 1979, he was appointed as Oxford'sRegius Professor of Medicine, succeedingRichard Doll.

Harris's research interests were primarily focused on cancer cells and their differences from normal cells. He later studied the possibility of genetic modification of human cell lines with the material of other species to increase the range of genetic markers. Harris and his colleagues developed some of the basic techniques for investigating and measuring genes along the humanchromosome.

In 1965, he reported his observation that most nuclearRNA was non-coding, a view that was not widely accepted until years later.[5] In 1969, Harris showed that when malignant cancer cells were fused with normalfibroblasts, the resulting hybrids were not malignant, thus demonstrating the existence of genes that could suppress malignancy. Work on thesetumour suppressor genes has become a worldwide industry.[citation needed]

In 1983, Harris was elected to theAustralian Academy of Science as a Corresponding Fellow. In 1993, he was knighted.[2]

Much of Harris's work has been supported byCancer Research UK (formerly the Cancer Research Campaign).[citation needed]

He died on 31 October 2014, aged 89.

Works

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Published books

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References

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  1. ^Watt, Fiona Mary (2015)."Professor Sir Henry Harris (1925–2014)"(PDF).Journal of Cell Science.128 (23): 4253.doi:10.1242/jcs.181859.PMID 26962590.
  2. ^abcThe Guardian. Retrieved 11 December 2014
  3. ^Gardner, Richard; Sidebottom, Eric (2018). "Sir Henry Harris. 28 January 1925—31 October 2014".Biographical Memoirs of Fellows of the Royal Society.doi:10.1098/rsbm.2018.0014
  4. ^http://www.shsobu.org.au/wp-content/uploads/imperial-honours.pdfArchived 23 March 2019 at theWayback Machine[bare URL PDF]
  5. ^Bryson, V; Vogel, HJ (1 January 1965). "Evolving Genes and Proteins".Science.147 (3653):68–71.Bibcode:1965Sci...147...68B.doi:10.1126/science.147.3653.68.PMID 17799782.

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