Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Hemoptysis

From Wikipedia, the free encyclopedia
Not to be confused withHematemesis.
Medical symptom consisting of bloody mucus from coughing
Medical condition
Hemoptysis
Other namesHaemoptysis, coughing up of blood
Lower left:Inflammation of thebronchus can bring about bloody mucus.
Pronunciation
SpecialtyPulmonology
SymptomsSpitting blood or bloody sputum
ComplicationsPulmonary aspiration,choking
Causesbronchitis,lung cancer, certaininfections,pulmonary embolism
Differential diagnosisepistaxis (combined withpost-nasal drip)

Hemoptysis orhaemoptysis is the discharge ofblood or blood-stainedmucus through the mouth coming from thebronchi,larynx,trachea, orlungs. It does not necessarily involve coughing. In other words, it is the airway bleeding. This can occur withlung cancer, infections such astuberculosis,bronchitis, orpneumonia, and certain cardiovascular conditions. Hemoptysis is considered massive at 300 mL (11 imp fl oz; 10 US fl oz). In such cases, there are always severe injuries. The primary danger comes fromchoking, rather thanblood loss.[1]

Diagnosis

[edit]
Diagnostic approach to solving the puzzle of hemoptysis.
  • Past history, history of present illness, family history[2]
    • history of tuberculosis, bronchiectasis, chronic bronchitis, mitral stenosis, etc.
    • history ofcigarette smoking, occupational diseases by exposure to silica dust, etc.
  • Blood
    • duration, frequency, amount
    • Amounts of blood: large amounts of blood, or there is blood-streaked sputum
    • Probable source of bleeding: Is the blood coughed up, or vomited?
  • Bloodysputum
    • color, characters: blood-streaked, fresh blood, frothy pink, bloody gelatinous.
  • Accompanying symptoms
    • fever, chest pain, coughing, purulent sputum, mucocutaneous bleeding, jaundice.
  • Imaging examination
    • chest X-ray, CT scan and 3D reconstruction images or CT virtual bronchoscopy, bronchial angiography.
  • Laboratory tests
    • blood test: WBC
    • Sputum: cells and bacterial examinations, sputum culture
  • Bronchial fiber endoscopy[3]

Differential diagnosis

[edit]

The most common causes for hemoptysis in adults are chest infections such asbronchitis orpneumonia.[1] In children, hemoptysis is commonly caused by the presence of aforeign body in theairway. Other common causes includelung cancers andtuberculosis. Less common causes includeaspergilloma,bronchiectasis,coccidioidomycosis,pulmonary embolism,pneumonic plague, andcystic fibrosis. Rarer causes includehereditary hemorrhagic telangiectasia (HHT or Rendu-Osler-Weber syndrome),Goodpasture's syndrome, andgranulomatosis with polyangiitis. A rare cause of hemoptysis in women isendometriosis, which leads to intermittent hemoptysis coinciding with menstrual periods in 7% of women with thoracic endometriosis syndrome.[4] Hemoptysis may be exacerbated or even caused by overtreatment withanticoagulant drugs such aswarfarin.[citation needed]

Blood-laced mucus from the sinus or nose area can sometimes be misidentified as symptomatic of hemoptysis (such secretions can be a sign of nasal orsinus cancer, but also asinus infection). Extensive non-respiratory injury can also cause one to cough up blood. Cardiac causes likecongestive heart failure andmitral stenosis should be ruled out. The origin of blood can be identified by observing its color. Bright-red, foamy blood comes from the respiratory tract, whereas dark-red, coffee-colored blood comes from thegastrointestinal tract. Sometimes hemoptysis may be rust-colored.[citation needed]

Massive hemoptysis and mortality

[edit]
Hemoptysis

Although there are reports that the fatality rate is as high as 80%, the mortality rate for hospitalized hemoptysis patients is 9.4% (withn=28539), calculated from the data in the article by Kinoshita et al.[27] This is probably the most reasonable figure considering the overwhelming number of cases.[citation needed]

The general definition of massive hemoptysis is more than 200 ml within 24 hours, but there is a wide range in the literature (100–600 ml). Considering that the total volume of the tracheal and bronchial lumen is about 150 cc,[28][29] it may be reasonable to define massive hemoptysis as 200 ml, which is a little more than 150 ml, in terms of setting the threshold for fatal hemoptysis. More than 400ml/day is not adequate for screening purposes.[citation needed]

Treatment

[edit]

Treatment depends on the underlying cause. Treatments include icedsaline, and topicalvasoconstrictors such asadrenaline orvasopressin.Tranexamic acid was proved to improve in-hospital mortality.[27] Selectivebronchial intubation can be used to collapse the lung that is bleeding. Also, endobronchial tamponade can be used.[30]Laser photocoagulation can be used to stop bleeding duringbronchoscopy.Angiography ofbronchial arteries can be performed to locate the bleeding, and it can often beembolized.[31]Bronchial artery embolization (BAE) is the first line treatment nowadays.[32][33][34][35][36] Surgical option is usually the last resort and can involveremoval of a lung lobe orremoval of the entire lung. Cough suppressants can increase the risk of choking.[1]

References

[edit]
  1. ^abcSabatine MS (2014).Pocket medicine (Fifth ed.). [S.l.]: Aspen Publishers, Inc.ISBN 978-1-4511-9378-7.
  2. ^"Hemoptysis".The Lecturio Medical Concept Library. Retrieved24 July 2021.
  3. ^Richard F.LeBlond (2004).Diagnostics. US: McGraw-Hill Companies, Inc.ISBN 978-0-07-140923-0.
  4. ^McCann MR, Schenk WB, Nassar A, Maimone S (September 2020)."Thoracic endometriosis presenting as a catamenial hemothorax with discordant video-assisted thoracoscopic surgery".Radiology Case Reports.15 (9):1419–1422.doi:10.1016/j.radcr.2020.05.064.PMC 7334551.PMID 32642009.
  5. ^Google Health – Google
  6. ^Google Health – Google
  7. ^"Sarcoidosis Signs & Symptoms – Sarcoidosis – HealthCommunities.com". Archived fromthe original on 2009-02-21. Retrieved2010-02-05.
  8. ^MedlinePlus Encyclopedia:Pulmonary aspergilloma
  9. ^Google Health – Google
  10. ^"Histoplasmosis Symptoms – Diseases and Conditions – Mayo Clinic".Archived from the original on 2013-05-31. Retrieved2010-02-05.
  11. ^"Pneumonia".The Lecturio Medical Concept Library. 27 August 2020. Retrieved1 July 2021.
  12. ^Dorland's illustrated medical dictionary (32nd ed.). Saunders/Elsevier. 2 May 2011. p. 593.ISBN 978-1-4160-6257-8.
  13. ^Ware LB, Matthay MA (December 2005). "Clinical practice. Acute pulmonary edema".N. Engl. J. Med.353 (26):2788–96.doi:10.1056/NEJMcp052699.PMID 16382065.
  14. ^"Endometriosis".The Lecturio Medical Concept Library. Retrieved25 July 2021.
  15. ^"Foreign Body Aspiration".The Lecturio Medical Concept Library. Retrieved25 July 2021.
  16. ^Pediatric Goodpasture Syndrome ateMedicine
  17. ^Altaie R, Ditizio F, Fahy GT (March 2005)."Microscopic polyangitis presenting with sub-acute reversible optic neuropathy".Eye (Lond).19 (3):363–5.doi:10.1038/sj.eye.6701479.hdl:10379/8830.PMID 15272290.
  18. ^"Granulomatosis with Polyangiitis".www.mayoclinic.org. Mayo Foundation for Medical Education and Research.Archived from the original on 22 December 2017. Retrieved3 March 2018.
  19. ^Adu, Emery & Madaio 2012, p. 125.
  20. ^Villa-Forte, Alexandra."Eosinophilic Granulomatosis with Polyangiitis (EGPA)".www.msdmanuals.com. Merck & Co. Retrieved7 September 2024.
  21. ^ab"Hemoptysis Causes – Hemoptysis – HealthCommunities.com". Archived fromthe original on 2009-01-23. Retrieved2010-02-05.
  22. ^abcd"Other Causes of Hemoptysis – Hemoptysis – HealthCommunities.com". Archived fromthe original on 2009-06-08. Retrieved2010-02-05.
  23. ^"Mitral Stenosis".The Lecturio Medical Concept Library. Retrieved24 July 2021.
  24. ^Jha, Suman K.; Karna, Bibek; Mahajan, Kunal (2020),"Tropical Pulmonary Eosinophilia",StatPearls, Treasure Island (FL): StatPearls Publishing,PMID 32491456, retrieved2020-12-01
  25. ^Hunt, Beverley J. (2014). "Bleeding and Coagulopathies in Critical Care".New England Journal of Medicine.370 (9):847–859.doi:10.1056/NEJMra1208626.ISSN 0028-4793.PMID 24571757.
  26. ^Hughes, JP; Stovin, PG (January 1959). "Segmental pulmonary artery aneurysms with peripheral venous thrombosis".British Journal of Diseases of the Chest.53 (1):19–27.doi:10.1016/S0007-0971(59)80106-6.PMID 13618502.
  27. ^abKinoshita T, Ohbe H, Matsui H, Fushimi K, Ogura H, Yasunaga H (November 2019)."Effect of tranexamic acid on mortality in patients with haemoptysis: a nationwide study".Critical Care.23 (1): 347.doi:10.1186/s13054-019-2620-5.PMC 6836388.PMID 31694697.
  28. ^Patwa A, Shah A (September 2015)."Anatomy and physiology of respiratory system relevant to anaesthesia".Indian Journal of Anaesthesia.59 (9):533–41.doi:10.4103/0019-5049.165849.PMC 4613399.PMID 26556911.
  29. ^Davidson K, Shojaee S (January 2020). "Managing Massive Hemoptysis".Chest.157 (1):77–88.doi:10.1016/j.chest.2019.07.012.PMID 31374211.S2CID 199388328.
  30. ^Valipour A, Kreuzer A, Koller H, Koessler W, Burghuber OC (June 2005)."Bronchoscopy-guided topical hemostatic tamponade therapy for the management of life-threatening hemoptysis".Chest.127 (6):2113–8.doi:10.1378/chest.127.6.2113.PMID 15947328.
  31. ^Hanson C, Karlsson CA, Kämpe M, Lamberg K, Lindberg E, Boman LM, Stålenheim G (August 2004). Guidelines for treatment of acute lung diseases (Report). Uppsala Academic Hospital.
  32. ^Woo S, Yoon CJ, Chung JW, Kang SG, Jae HJ, Kim HC, et al. (November 2013). "Bronchial artery embolization to control hemoptysis: comparison of N-butyl-2-cyanoacrylate and polyvinyl alcohol particles".Radiology.269 (2):594–602.doi:10.1148/radiol.13130046.PMID 23801773.S2CID 21597160.
  33. ^Ishikawa H, Hara M, Ryuge M, Takafuji J, Youmoto M, Akira M, et al. (February 2017)."Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study".BMJ Open.7 (2) e014805.doi:10.1136/bmjopen-2016-014805.PMC 5318547.PMID 28213604.
  34. ^Ryuge M, Hara M, Hiroe T, Omachi N, Minomo S, Kitaguchi K, et al. (February 2019)."Mechanisms of recurrent haemoptysis after super-selective bronchial artery coil embolisation: a single-centre retrospective observational study".European Radiology.29 (2):707–715.doi:10.1007/s00330-018-5637-2.PMC 6302874.PMID 30054792.
  35. ^Panda A, Bhalla AS, Goyal A (2017-07-07)."Bronchial artery embolization in hemoptysis: a systematic review".Diagnostic and Interventional Radiology.23 (4):307–317.doi:10.5152/dir.2017.16454.PMC 5508955.PMID 28703105.
  36. ^Olsen KM, Manouchehr-Pour S, Donnelly EF, Henry TS, Berry MF, Boiselle PM, et al. (May 2020). "ACR Appropriateness Criteria® Hemoptysis".Journal of the American College of Radiology.17 (5S):S148 –S159.doi:10.1016/j.jacr.2020.01.043.PMID 32370959.S2CID 218520816.

Further reading

[edit]

External links

[edit]
Classification
External resources
Auscultation
Breathing
Rate
Pattern
Other
Vocal fold
Other
Disorders ofbleeding andclotting
Clotting
By cause
Clots
By site
Bleeding
By cause
Thrombocytopenia
Platelet function
Clotting factor
Signs and symptoms
By site
Authority control databases: NationalEdit this at Wikidata
Retrieved from "https://en.wikipedia.org/w/index.php?title=Hemoptysis&oldid=1322481824"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp