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Names | |
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IUPAC name (1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol | |
Other names 1-Hydroxyergocalciferol; 1-Hydroxyvitamin D2; 1α-Hydroxyergocalciferol; 1α-Hydroxyvitamin D2; Hectorol; TSA 840 | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
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DrugBank |
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ECHA InfoCard | 100.170.997![]() |
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Properties | |
C28H44O2 | |
Molar mass | 412.658 g·mol−1 |
Pharmacology | |
H05BX03 (WHO) | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). |
Doxercalciferol (or1-hydroxyergocalciferol, trade nameHectorol) is drug forsecondary hyperparathyroidism andmetabolic bone disease.[1] It is a synthetic analog ofergocalciferol (vitamin D2). It suppressesparathyroid synthesis and secretion.[2]
Doxercalciferol is the vitamin D2 analogue ofalfacalcidol.[3] It undergoes 25-hydroxylation in theliver to become the activeercalcitriol, without the involvement of kidneys.[4]
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