Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Hartmut Michel

From Wikipedia, the free encyclopedia
German biochemist (born 1948)
Hartmut Michel
Hartmut Michel in 2013
Born (1948-07-18)18 July 1948 (age 77)
NationalityGerman
Alma materUniversity of Tübingen
Known forCrystallisation ofmembrane proteins
SpouseElena Olkhova
Awards
Scientific career
FieldsBiochemistry
InstitutionsMax Planck Institute for Biophysics
Websitewww.biophys.mpg.de/en/michel.html

Hartmut Michel (German pronunciation:[ˈhaʁtmuːtˈmɪçl̩]; born 18 July 1948) is a Germanbiochemist, who received the 1988Nobel Prize in Chemistry for determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential tophotosynthesis.[2][3][4][5]

Education and early life

[edit]

He was born on 18 July 1948 inLudwigsburg. After compulsory military service, he studied biochemistry at theUniversity of Tübingen, working for his final year at Dieter Oesterhelt's laboratory onATPase activity ofhalobacteria.

Career and research

[edit]

Hartmut later[when?] worked on the crystallisation ofmembrane proteins – essential for their structure elucidation byX-ray crystallography. He received theNobel Prize jointly withJohann Deisenhofer andRobert Huber in 1988. Together with Michel and Huber, Deisenhofer determined the three-dimensional structure of a protein complex found in certain photosynthetic bacteria. This membrane protein complex, called aphotosynthetic reaction center, was known to play a crucial role in initiating a simple type of photosynthesis. Between 1982 and 1985, the three scientists usedX-ray crystallography to determine the exact arrangement of the more than 10,000 atoms that make up the protein complex. Their research increased the general understanding of the mechanisms of photosynthesis, revealed similarities between the photosynthetic processes of plants and bacteria and established a methodology for crystallising membrane proteins.[6]

Since 1987 he has been director of the Molecular Membrane Biology department attheMax Planck Institute for Biophysics inFrankfurt am Main, Germany, and professor of biochemistry at theGoethe University Frankfurt.

Awards and honours

[edit]

In 1986, he received theGottfried Wilhelm Leibniz Prize of theDeutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. In 1988, he received theNobel Prize in Chemistry. He received the Bijvoet Medal at theBijvoet Center for Biomolecular Research ofUtrecht University in 1989.[7] In 1995 he became a member of theGerman Academy of Sciences Leopoldina.[8] He also became a foreign member of theRoyal Netherlands Academy of Arts and Sciences in 1995.[9] He was elected aForeign Member of the Royal Society (ForMemRS) in 2005.[1]

References

[edit]
  1. ^ab"Professor Hartmut Michel ForMemRS". London:Royal Society. Archived fromthe original on 26 October 2015.
  2. ^"Autobiographical information on Hartmut at www.nobel.org". Retrieved4 October 2021.
  3. ^"P3 Hartmut Michel".www.sfb807.de. Archived fromthe original on 3 March 2017. Retrieved30 March 2011.
  4. ^Iwata, S.; Ostermeier, C.; Ludwig, B.; Michel, H. (1995). "Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans".Nature.376 (6542):660–9.Bibcode:1995Natur.376..660I.doi:10.1038/376660a0.PMID 7651515.S2CID 4345523.
  5. ^Deisenhofer, J.; Epp, O.; Miki, K.; Huber, R.; Michel, H. (1984). "X-ray structure analysis of a membrane protein complex".Journal of Molecular Biology.180 (2):385–98.doi:10.1016/S0022-2836(84)80011-X.PMID 6392571.
  6. ^Deisenhofer, J.; Epp, O.; Miki, K.;Huber, R.;Michel, H. (1985). "Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution".Nature.318 (6047):618–24.Bibcode:1985Natur.318..618D.doi:10.1038/318618a0.PMID 22439175.S2CID 1551692.
  7. ^"Bijvoet Medal". Bijvoet Center for Biomolecular Research. Archived fromthe original on 12 September 2017. Retrieved12 September 2017.
  8. ^"Hartmut Michel". German Academy of Sciences Leopoldina. Retrieved1 June 2021.
  9. ^"H. Michel". Royal Netherlands Academy of Arts and Sciences. Archived fromthe original on 13 February 2016. Retrieved13 February 2016.

External links

[edit]
1901–1925
1926–1950
1951–1975
1976–2000
2001–present
1988Nobel Prize laureates
Chemistry
Literature (1988)
Peace
Physics
Physiology or Medicine
Economic Sciences
Fellows
Foreign
Honorary
International
National
Academics
People
Other

Retrieved from "https://en.wikipedia.org/w/index.php?title=Hartmut_Michel&oldid=1280369782"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp