Protein-coding gene in the species Homo sapiens
Voltage-gated hydrogen channel 1 is aprotein that in humans is encoded by theHVCN1 gene .
Voltage-gated hydrogen channel 1 is avoltage-gated proton channel that has been shown to allow proton transport intophagosomes [ 5] [ 6] spermatozoa ,electrically excitable cells andrespiratory epithelial cells.[ 7] voltage-gated potassium channels andvoltage-gated sodium channels .[ 8] water wire " for allowing hydrogen bonded H+ to cross the membrane.[ 9] [ 10] [ 11] [ 12] [ 13] [ 14] [ 15]
Small molecule inhibitors of the HVCN1 channel are being developed aschemotherapeutics andanti-inflammatory agents.[ 16]
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