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HU-320

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
HU-320
Identifiers
  • (3S,4S)-3-[2,6-Dihydroxy-4-(2-methyloctan-2-yl)phenyl]-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic acid
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC25H36O4
Molar mass400.559 g·mol−1
3D model (JSmol)
  • O=C(O)/C2=C/[C@H](c1c(O)cc(cc1O)C(C)(C)CCCCCC)[C@@H](\C(=C)C)CC2
  • InChI=1S/C25H36O4/c1-6-7-8-9-12-25(4,5)18-14-21(26)23(22(27)15-18)20-13-17(24(28)29)10-11-19(20)16(2)3/h13-15,19-20,26-27H,2,6-12H2,1,3-5H3,(H,28,29)/t19-,20+/m1/s1 checkY
  • Key:LDMILSDGSQMZOB-UXHICEINSA-N checkY
  (verify)

HU-320 (7-nor-7-carboxy-CBD-1,1-DMH) is a drug related tocannabidiol, which has strongantiinflammatory andimmunosuppressive properties while demonstrating nopsychoactive effects.[1][2]

See also

[edit]

References

[edit]
  1. ^Sumariwalla PF, et al. (2004)."A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis".Arthritis Rheum.50 (3):985–998.doi:10.1002/art.20050.PMID 15022343.
  2. ^Hanus LO, Tchilibon S, Ponde DE, Breuer A, Fride E, Mechoulam R (Mar 2005). "Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors".Org Biomol Chem.3 (6):1116–23.doi:10.1039/b416943c.PMID 15750656.
Phytocannabinoids
(comparison)
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AllostericCBRTooltip Cannabinoid receptorligands
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(inactivation inhibitors)
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