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HIV/AIDS in the United Kingdom

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Thefactual accuracy of parts of this article (those related to new report - see talk)may be compromised due to out-of-date information. Please help update this article to reflect recent events or newly available information.(December 2021)
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342MSM activitymade illegal
1533Death penalty introduced for MSM activity
1543 Buggery Act extended to Wales
1828Offences Against the Person Act 1828
1835James Pratt and John Smith executed
1861Death penalty for buggery abolished
1885Labouchere Amendment introduced
1889Cleveland Street scandal
1895Oscar Wilde found guilty of gross indecency
1912The Cave of the Golden Calf opens
1921 Plans to make lesbian activity illegal defeated
1936Mark Weston transitions
1952John Nott-Bower begins crackdown
1954Pitt-Rivers,Montagu,Wildeblood imprisoned
1954Alan Turing commits suicide
1957Wolfenden report released
1967MSM activity made legal (England & Wales)
1972 First BritishGay Pride Rally
1976Jeremy Thorpe resigns as Liberal leader
1981 MSM activitymade legal (Scotland)
1981 First case ofAIDS reported in the UK
1982 MSM activitymade legal (NI)
1983 Gay menbarred from donating blood
1984Chris Smith elected as first openly gay MP
1987Operation Spanner begins
1988Section 28 comes into force
1989Stonewall UK forms
1994 Age of consent for MSM becomes 18
1997Angela Eagle becomes first openly lesbian MP
1998Bolton 7 found guilty
1998Lord Alli becomes first openly gay Lord
1999Admiral Duncan bombing
2000 Gay men allowed in HM Armed Forces
2001 Age of consent equalised to 16
2001 MSM activity involving multiple men legal
2002 Same sex couples grantedequal rights to adopt
2003 Section 28 repealed
2004 Civil partnerships introduced
2004Gender Recognition Act 2004
2006 Discriminationmade illegal
2008Equalised access to IVF for lesbian couples
2008 Incitement to homophobic hatred made a crime
2009 Public apology toAlan Turing
2010Equality Act 2010
2011 Gay men allowed to donate blood (1 yr deferral)
2013Nikki Sinclaire becomes first openly trans MEP
2013Marriage (Same Sex Couples) Act 2013
2014 Firstsame-sex marriages take place
2016 MSM activity not grounds for military discharge
2017Turing law implemented
2017 Blood donation deferral 3 months (excl. NI)
2019 MPslegislate forgay marriage in NI
2020Gay marriage legal across UK, incl. NI
2020 Blood donation deferral 3 months (incl. NI)
2021Blood donation deferral equalised

AIDS was first diagnosed in 1981. As of year-end 2018, 160,493 people have been diagnosed with HIV in the United Kingdom and an estimated 7,500 people are living undiagnosed with HIV.[1] New diagnoses are highest in gay/bisexual men, with an estimated 51% of new diagnosis reportingmale same-sex sexual activity as the probable route of infection. Between 2009 and 2018 there was a 32% reduction in new HIV diagnosis, attributed byPublic Health England (PHE) to bettersurveillance and education.[1] PHE has described an "outbreak" in Glasgow amongstpeople who inject drugs,[1] and has campaigns targetingmen who have sex with men inLondon and other major cities.[2] London was the first city in the world to reach theWorld Health Organization target for HIV, set at 90% of those with HIV diagnosed, 90% of those diagnosed onHAART and 90% of those on HAART undetectable.[2][3] The UK as a whole later achieved the same target.[3] Under theEquality Act 2010, it is illegal to discriminate against someone based on their HIV status in the UK.[4][5]

Demographics

[edit]

In 2017, 93,385 people (64,472 men and 28,877 women) living with diagnosed HIV infection received HIV care in the UK. 42,739 of those are gay or bisexual.[6]

In 2017, the prevalence ofHIV in theUnited Kingdom was estimated at 101,600 (credible interval 99,300 to 106,400) with 92% (credible interval 88 to 94%) diagnosed.[6] Prevalence is highest in gay/bisexual men inLondon with an estimated 83 (credible interval 73 to 96) per 1000 gay and bisexual men aged 15 to 74 years. HIV prevalence in this group was higher in London compared with the rest of England (134/1,000 CrI 113 to 156 and 63/1,000 CrI 53 to 76, respectively).[6] However, the 2017 statistics showed a tremendous decrease in the number of newly HIV infected gay men during 2015-17. The number of newly HIV infected gay men decreased by a third in just two years.[7]

2995 people were newly diagnosed during 2021[8] An estimated 42% of diagnoses were late (likely to have been living with the virus for over three years). Late diagnosis is associated with a 10-fold increase in the chance of death during the first year after diagnosis.[9][10] Risk groups have been identified by various organisations, includingNational Institute for Health and Care Excellence,National Health Service and the IMPACT trial for pre-exposure prophylaxis. They are:

Risk groups identified by UK health organisations
NHS for HIV[11][12]NICE for HIV testing[13]IMPACT for PrEP access[14]
From a country with high rates of HIVHeterosexual people at risk
People who share needlesPeople who inject drugs
People who have received a blood transfusion abroad
Heterosexual with black African ethnicity☒N☒N
Men who have sex with men
Trans women who have sex with menTrans men and trans women
People who participate in chemsex☒N
People diagnosed with any other STI☒N
Sexual contact with any other risk groupHIV-negative people with HIV-positive partners

Treatment and prognosis

[edit]
HIV & AIDS Diagnoses and Deaths by Year in the UK

HIV treatment is available free of charge in the UK and as a result 96% of diagnosed are receiving treatment and of those 94% have a suppressed viral load making them very unlikely to pass on the infection.[15][9][16] In 2015, less than 1% of people living with a diagnosed HIV infection in the UK died (cause of death is uncertain and may not be HIV-related). All-cause mortality for ages 15–59 in people living with HIV was 5.7 per 1000 compared to 1.7 for the UK population as a whole.[9] People newly diagnosed with HIV today can expect to have a normal life expectancy if they are diagnosed on time and on effective treatment.[17]

In 2017, 39% adults seen for HIV care were 50 years of age or older.[6] This is partly due to improvements to life expectancy for people living with HIV as well as increasing numbers of people acquiring HIV later in life.[citation needed]

Pre-exposure prophylaxis

[edit]
See also:National AIDS Trust v NHS Commissioning Board
Thefactual accuracy of parts of this article (those related to Pre-exposure prophylaxis)may be compromised due to out-of-date information. Please help update this article to reflect recent events or newly available information.(May 2021)

Access topre-exposure prophylaxis ("PrEP"), using a drug which can prevent HIV infection, on theNational Health Service is partially limited. It was available to high-risk individuals in England through the IMPACT trial, which had a cohort size of 26,000.[18] This was made available following the PROUD trial, arandomised control trial and ahigh-court battle in 2016.[19][20] Use of PrEP in London, both as part of a trial and from private purchases, was partially credited in a drop in diagnoses among men who have sex with men, after a five-year plateau in diagnoses.[21][22][23]

InScotland, England, Wales and Northern Ireland PrEP is available free on the NHS fromsexual health clinics for those deemed at high risk of acquisition.[1]

Sexual health specialistMags Portman was credited in making PrEP more accessible to gay and bisexual men in the UK. In October 2018, theTerrence Higgins Trust established the Mags Portman PrEP Access Fund to provide PrEP to those in England and Northern Ireland who cannot afford it.[24] The fund has a maximum size of 1,000 users and was available until the end of 2020.[25]

Timeline

[edit]

1979, June: a sample shows a UK transmission to a haemophiliac in the UK.[26]

1981, 12 December:The Lancet publishes a case report of a 49-year-old man who had died inBrompton hospital due to an AIDS related illness in October - the first death in the UK.[27][28] He was homosexual and a frequent visitor to the United States.[29]

It was finally revealed in November 2021, by the ITV Tonight programme that this first patient was called John Eaddie, a 49 year old guest house proprietor from Harrogate - 40 years after the first mention of a case in a medical journal.[30]Painstaking work from the ITV Tonight team matched a death certificate from 1981, which included the same details revealed in the Lancet - a 49 year old man, dying in the Royal Brompton Hospital of Pneumocystis Pneumonia.[citation needed]

1982, 4 July:Terry Higgins dies of an AIDS related illness - leading to the establishment of theTerrence Higgins Trust.[31][32]

1983:Scottish AIDS Monitor founded to monitor and raise awareness of HIV/AIDS in Scotland.[33]

1983, 25 April:BBC broadcasts "Killer in the Village" as part of itsHorizon series. The documentary describes the illnesses affecting patients and looks at theories and early research into AIDS. It includes interviews withLinda Laubenstein, Alvin Friedman-Kien,James W. Curran,Michael S. Gottlieb andBobbi Campbell.

1985: 58 AIDS-related deaths had been recorded in Britain,[34] according to the current affairs seriesTV Eye, broadcast in 1985. In October, a man with AIDS is detained under thePublic Health (Infectious Diseases) Regulations 1985, marking their first and only use.[35]

1986, 24 March:BBC broadcasts "AIDS: A Strange and Deadly Virus" as part of itsHorizon series. The documentary looks at early work to identify the virus and experimental use ofAZT.

1987, 9 April:Diana, Princess of Wales, opens theBroderip Ward, a dedicated ward atMiddlesex Hospital for the treatment of HIV patients, and notably shakes the hands of AIDS patients without wearing gloves.[36][37][38]

1987: The UK Government launched "AIDS: Don't Die of Ignorance", a major public information campaign. A leaflet about AIDS was delivered to every household in the UK, which warned that it is impossible to tell who is infected with the virus.[39]

1991, 24 November:Queen starFreddie Mercury dies of AIDS, just one day after he announced he had the condition.[40]

1994: Scottish Voluntary HIV and AIDS Forum (HIV Scotland) set up in Edinburgh to make policy and advocacy changes and provide support for people living with HIV in Scotland.[41]

1995: Project for HIV and Aids Care and Education (PHACE West) established to provide HIV support, advice and health services for the West of Scotland.[42]

1996: Triple combination therapy (HAART) becomes standard treatment, reducing the death rate.[43][44]

2003, March : TheNational AIDS Trust launched a campaign challenging HIV stigma.[45]

2010, 8 April: TheEquality Act 2010 qualifies anyone with HIV as disabled and so gives protection against discrimination.[4][5]

2012: 1 October: Free HIV treatment in England extended to include non-resident overseas visitors.[46][47]

2012, 23 November: First National HIV Testing Week.[48][49]

2013, April: HIV Prevention England started a two-year campaign funded by theDepartment of Health communicating messages about HIV testing and condoms to Africans and MSM.

2015, April: First home testing kits become available, after being legalised in April 2014.[50]

2015, 9 September: Results announced of PROUD study, testing the effectiveness of PrEP on reducing HIV infections in 544 participants.[51][52]

2016: Results of PARTNER Study show that a person living with HIV, who is on treatment and whose virus is undetectable cannot pass the virus on to anyone else. The 'U=U' campaign and Terrence Higgins Trust's 'Can't Pass It On' campaigns followed shortly after. The PARTNER Study followed other research and studies, such as the Swiss Statement, which provided similar evidence of HIV not being able to be passed on under these stated circumstances.[53]

2017, July:PrEP made available free on the NHS in Scotland.[54]

2017, 3 August: NHS announced trial of PrEP for 10,000 people over three years.[55]

2019, 1 January: NHS announced to increase IMPACT trial size to 26,000.

2019, 22 July: IndependentHIV CommissionArchived 2020-06-21 at theWayback Machine to end new HIV transmissions in England by 2030 launches.[56]

2020, March: UK government announces PrEP will be made freely available in England from April 2020 to anyone at risk.[57]

2021, 1 December: the UKMinistry of Defence announces a commitment to ensuring being HIV+ no longer excludes anyone from joining the armed forces. Any candidates taking PrEP would be welcomed and serving armed forces personnel with HIV are recognised as fully fit.[58]

2022: Accident and Emergency treatment will have opt out testing for blood bourne viruses, a pilot study identified 65 people with HIV not undergoing treatment. In 2023 it was decided to extend this to all hospital settings.[59]

See also

[edit]

References

[edit]
  1. ^abcdPublic Health England (December 2019)."HIV in the UK (2019 Report)"(PDF).gov.uk. Retrieved2020-02-21.
  2. ^abGulland, Anne (2019-09-09)."London praised for record on HIV but more needs to be done to tackle late diagnosis".The Telegraph.ISSN 0307-1235. Retrieved2020-02-21.
  3. ^ab"UK HIV Statistics | National AIDS Trust - NAT".www.nat.org.uk. Retrieved2020-02-21.
  4. ^abTrust, Terrence Higgins."Equality Act 2010 | Terrence Higgins Trust".Tht.org.uk. Retrieved2017-08-29.
  5. ^ab"Equality Act 2010".Legislation.gov.uk. Expert Participation. Retrieved2017-08-29.{{cite web}}: CS1 maint: others (link)
  6. ^abcd"Progress towards ending the HIV epidemic in the United Kingdom 2018 report )"(PDF).Public Health England. 2018. Retrieved2019-06-25.
  7. ^"HIV diagnoses in gay men in the UK decreased by a third in two years".Aidsmap.com. 4 September 2018. Retrieved5 March 2019.
  8. ^TheGuardian.comhttps://www.theguardian.com/society/2022/oct/22/no-new-hiv-cases-by-2030-england-hopes-to-become-first-country-in-the-world-to-defeat-virus. Retrieved22 October 2022.{{cite web}}:Missing or empty|title= (help)
  9. ^abc"HIV in the UK"(PDF).UK Government. Public Health England. 2016-12-01. Retrieved2017-08-27.
  10. ^"HIV: surveillance, data and management".Gov.uk. 25 January 2018. Retrieved5 March 2019.
  11. ^"HIV and AIDS - Causes".nhs.uk. 2017-10-23. Retrieved2020-02-21.
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  13. ^"Quality statement 4: Regular HIV testing | HIV testing: encouraging uptake | Quality standards | NICE".www.nice.org.uk. 7 September 2017. Retrieved2020-02-21.
  14. ^"Can I take part?".PrEP Impact. Retrieved2020-02-21.
  15. ^Trust, Terrence Higgins."Effective HIV treatment means 'zero' risk of transmitting virus | Terrence Higgins Trust".Tht.org.uk. Archived fromthe original on 2017-08-27. Retrieved2017-08-27.
  16. ^Trust, Terrence Higgins."Can't Pass It On | Terrence Higgins Trust".Tht.org.uk. Retrieved2017-08-27.
  17. ^Roxby, Philippa (2017-05-11)."HIV life expectancy 'near normal' thanks to new drugs".BBC News. Retrieved2017-08-26.
  18. ^"PrEP | The PrEP Impact Trial".PrEP Impact. Retrieved2020-02-21.
  19. ^Gallagher, James (2017-08-03)."Prep: HIV 'game-changer' to reach NHS in England from September".BBC News. Retrieved2017-08-26.
  20. ^"HIV campaigners win NHS drug battle".BBC News. 2016-08-02. Retrieved2017-08-26.
  21. ^"Meet The Man Who Stopped Thousands Of People Becoming HIV-Positive".BuzzFeed. Retrieved2017-08-26.
  22. ^"'Remarkable' drop in new HIV cases among men".BBC News. 2017-06-22. Retrieved2017-08-26.
  23. ^editor, Sarah Boseley Health (2017-06-22)."Fall in HIV among gay men could spell end for Britain's epidemic, say experts".The Guardian.ISSN 0261-3077. Retrieved2017-08-27.{{cite news}}:|last= has generic name (help)
  24. ^Ledward, James (30 October 2018)."THT launch 'Access Fund' for PrEP".Gscene.com. Retrieved12 February 2019.
  25. ^"The Mags Portman PrEP Access Fund | Terrence Higgins Trust".www.tht.org.uk. Retrieved2020-02-21.
  26. ^"Final Report: Chapter 9 - Knowledge of the Geographical Spread and Prevalence of HIV/AIDS 1".www.penroseinquiry.org.uk. Retrieved2020-02-21.
  27. ^Bois, R. M. Du; Branthwaite, M. A.; Mikhail, J. R.; Batten, J. C. (1981-12-12). "Primary Pneumocystis Carinii and Cytomegalovirus Infections".The Lancet. Originally published as Volume 2, Issue 8259.318 (8259): 1339.doi:10.1016/S0140-6736(81)91353-2.PMID 6118728.S2CID 38202095.
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  31. ^"How It All Began".Terrance Higgins Trust. Archived fromthe original on 2015-07-15. Retrieved2016-08-29.
  32. ^Prior, Neil (2012-07-05)."Terrence Higgins' legacy, 30 years after death".BBC News. Retrieved2017-08-29.
  33. ^"1980s".Terrance Higgins Trust. Retrieved2 February 2021.
  34. ^"Watch AIDS: The Victims 1985".BFI. Retrieved2021-01-27.
  35. ^"Public Health (Infectious Diseases) Regulations 1985".Europach. Retrieved24 February 2021.
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  37. ^"BBC NEWS | Health | Timeline: 25 years of HIV/Aids".News.bbc.co.uk. 4 June 2006. Retrieved2017-08-29.
  38. ^"Prince Harry invokes image of Princess Diana holding hand of dying Aids patient as he warns of HIV complacency threat".The Telegraph. Retrieved2017-08-29.
  39. ^Hildrew, Peter."From the archive, 9 January 1987: TV and cinema Aids campaign launches".The Guardian. Retrieved24 October 2014.
  40. ^"Queen star dies after Aids statement | 1990-1999 | Guardian Century".Theguardian.com. Retrieved2017-08-29.
  41. ^"Our history".HIV Scotland. Retrieved2021-02-02.
  42. ^"Back in the hot seat".Gay Scotland. No. 20. 1985.
  43. ^Trust, Terrence Higgins."Terrence Higgins Trust in the 1990s | Terrence Higgins Trust".Tht.org.uk. Retrieved2017-08-29.
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  46. ^"HIV treatment for overseas visitors in England from 1 October 2012".Gov.uk. Retrieved2017-08-29.
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  48. ^"Ready to Be Tested? England's First National HIV Testing Week Starts Today".Huff Post. 23 November 2012. Retrieved2017-08-29.
  49. ^Tom Hayes (2012-11-23)."National HIV Testing Week".Beyondpositive. Archived fromthe original on 2017-08-29. Retrieved2017-08-29.
  50. ^Mundasad, Smitha (2015-04-27)."HIV home test kit goes on sale in UK".BBC News. Retrieved2017-08-29.
  51. ^McCormack, Sheena; Dunn, David T.; Desai, Monica; Dolling, David I.; Gafos, Mitzy; Gilson, Richard; Sullivan, Ann K.; Clarke, Amanda; Reeves, Iain (2016-01-02)."Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial".The Lancet.387 (10013):53–60.doi:10.1016/S0140-6736(15)00056-2.ISSN 0140-6736.PMC 4700047.PMID 26364263.
  52. ^"PROUD PrEP study results published".Aidsmap.com. Retrieved2017-08-29.
  53. ^"HIV & AIDS Information :: NAM endorses Undetectable equals Untransmittable (U=U) consensus statement". Archived fromthe original on 2018-07-17. Retrieved2018-07-17.
  54. ^National Services Scotland, NHS (February 2019)."Implementation of HIV PrEP in Scotland: first year report". Archived fromthe original on 2021-02-08.
  55. ^"NHS England » NHS England announces world's largest single PrEP implementation trial to prevent HIV infection".England.nhs.uk. Retrieved2017-08-29.
  56. ^Guerra, Luis (2019-07-22)."New independent HIV Commission to end HIV transmissions in England by 2030 launches with Government endorsement".HIV Commission. Archived fromthe original on 2020-06-18. Retrieved2020-06-18.
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  59. ^"Emergency department opt out testing for HIV, hepatitis B and hepatitis C: The first 100 days". November 22, 2023. RetrievedJan 1, 2024.
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