Guo had an eventful semi-final in the sprint at the2008 Summer Olympics, having won the first heat and conceded the second to her opponentAnna Meares, the third heat saw Guo come down the banking too steeply and her front wheel slipped from beneath her. The heat was re-run and although Guo won by a few millimetres, she was relegated for coming down the tack and pushing Meares onto thecôte d'azure on the final lap. This put Meares through to the final ride-off for gold. Guo went on to win the final ride-off for the bronze againstWilly Kanis.
Guo competed in the2012 Summer Olympics in London.[2] She andGong Jinjie set aworld record of 32.447 seconds in the qualification round of the team sprint event, which they then improved upon with 32.422 in the next round.[3] They went on to finish first in the final against the German team, but were disqualified for an early relay, and were relegated to the silver medal instead.[4] Guo and Gong's coachDaniel Morelon maintains that the pair were "robbed" of the gold medal, and described it as an "injustice". He complained that the judges refused to provide a "video footage of the race on slow motion", and only provided a "vague explanation" for the infringement they had allegedly committed.[5] However, the British cycling championsVictoria Pendleton andJessica Varnish, who were also disqualified for a similar reason earlier on in the competition, accepted the judges decision and chose not to claim that they were unfairly robbed of a medal.[6] Pendleton recovered and went on to win a gold medal in the women'skeirin event with Guo Shuang coming 2nd.[7]