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| Names | |
|---|---|
| IUPAC name 6′′,6′′-Dimethyl-6′′H-pyrano[2′′,3′′:2′,3′]isoflav-3-ene-4′,7-diol | |
| Systematic IUPAC name 2′,2′-Dimethyl-2H,2′H-[3,8′-bi-1-benzopyran]-5′,7-diol | |
| Other names 2',2'-dimethyl-2H,2'H-3,8'-bichromene-5',7-diol | |
| Identifiers | |
3D model (JSmol) | |
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| Properties | |
| C20H18O4 | |
| Molar mass | 322.36 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Glabrene is anisoflavonoid that is found inGlycyrrhiza glabra (licorice).[1] It hasestrogenic activity, showing estrogenic effects onbreast,vascular, andbonetissue, and hence is aphytoestrogen (IC50 forestrogen receptor binding = 1 μM).[1][2][3] It has also been found to act as atyrosinaseinhibitor (IC50 = 3.5 μM) and to inhibit the formation ofmelanin inmelanocytes, and for these reasons, has been suggested as a potential skin-lightening agent.[4]
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