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| Clinical data | |
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| Other names | Gestonorone; 17α-Hydroxy-19-norprogesterone; 17α-Hydroxy-19-norpregn-4-ene-3,20-dione |
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| CAS Number | |
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| ECHA InfoCard | 100.016.708 |
| Chemical and physical data | |
| Formula | C20H28O3 |
| Molar mass | 316.441 g·mol−1 |
| 3D model (JSmol) | |
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Gestronol (BANTooltip British Approved Name), also known asgestonorone, as well as17α-hydroxy-19-norprogesterone or17α-hydroxy-19-norpregn-4-ene-3,20-dione, is aprogestin of the19-norprogesterone and17α-hydroxyprogesterone groups which was never marketed.[1][2][3] The C17αcaproateester of gestronol,gestonorone caproate (gestronol hexanoate), in contrast, has been marketed.[1][2][3]
Gestronol shows relatively lowaffinity for theprogesterone receptor, only about 12.5% of that ofprogesterone and about 2.5% of that of19-norprogesterone in oneassay.[4] On the other hand, gestronol had far higher affinity than17α-hydroxyprogesterone, which showed less than 0.1% of the affinity of progesterone for the progesterone receptor.[4]
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