Gallopamil

Clinical data
Other names	Methoxyverapamil
AHFS/Drugs.com	International Drug Names
ATC code	C08DA02 (WHO)
Identifiers
IUPAC name (RS)-5-[2-(3,4-Dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
CAS Number	16662-47-8 Y HCl: 16662-46-7 Y
PubChemCID	1234
ChemSpider	1197 Y
UNII	39WPC8JHR8 HCl: VT4VR32A0T Y (HCl)
KEGG	D01969 Y
ChEMBL	ChEMBL51149 Y
CompTox Dashboard(EPA)	DTXSID5045172
Chemical and physical data
Formula	C28H40N2O5
Molar mass	484.637 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES N#CC(c1cc(OC)c(OC)c(OC)c1)(CCCN(CCc2ccc(OC)c(OC)c2)C)C(C)C
InChI InChI=1S/C28H40N2O5/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5/h10-11,16-18,20H,9,12-15H2,1-8H3 Y Key:XQLWNAFCTODIRK-UHFFFAOYSA-N Y

Gallopamil (INN) is an L-typecalcium channel blocker that is an analog ofverapamil. It is used in the treatment ofabnormal heart rhythms.^[1]

Thealkylation reaction of 3,4,5-trimethoxyphenylacetonitrile (1) andisopropyl chloride (2), usingsodium amide as base gives the intermediatenitrile (3). A second alkylation with a specificalkyl chloride (4) yields gallopamil.^[2][3][4]

Thisdrug article relating to thecardiovascular system is astub. You can help Wikipedia byexpanding it.

• v
• t
• e

• Calcium channel blockers
• Pyrogallol ethers
• Nitriles
• Methoxyphenethylamines
• Isopropyl compounds
• Cardiovascular system drug stubs

• Articles with short description
• Short description is different from Wikidata
• Chemical pages without DrugBank identifier
• Multiple chemicals in Infobox drug
• Chemicals using indexlabels
• Chemical articles with multiple CAS registry numbers
• Drugs with no legal status
• Articles containing unverified chemical infoboxes
• All stub articles