GSK417651A

Identifiers
IUPAC name 3,4-dihydro-1H-isoquinolin-2-yl-[2-(4-methoxyanilino)-1,3-thiazol-4-yl]methanone
CAS Number	736945-96-3 Y
PubChemCID	1096735
UNII	WV82DEG4YA
CompTox Dashboard(EPA)	DTXSID701336625
Chemical and physical data
Formula	C20H19N3O2S
Molar mass	365.45 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC=C(C=C1)NC2=NC(=CS2)C(=O)N3CCC4=CC=CC=C4C3
InChI InChI=1S/C20H19N3O2S/c1-25-17-8-6-16(7-9-17)21-20-22-18(13-26-20)19(24)23-11-10-14-4-2-3-5-15(14)12-23/h2-9,13H,10-12H2,1H3,(H,21,22) Key:NTXBDULODNTCKP-UHFFFAOYSA-N

GSK417651A is a chemical compound which acts as a blocker of theTRPC family of calcium channels, with selectivity for theTRPC3 andTRPC6 subtypes. It has been used to investigate the role of TRPC3/6 channels in heart function.^[1][2][3]

• Thiazoles
• Ketones
• Nitrogen heterocycles
• Secondary amines

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