GSK1016790A

Identifiers
IUPAC name N-[(1S)-1-[[4-[(2S)-2-[[(2,4-Dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]benzo[b]thiophene-2-carboxamide
CAS Number	942206-85-1
PubChemCID	23630211
ChemSpider	29310491
ChEBI	CHEBI:140524
CompTox Dashboard(EPA)	DTXSID30635248
Chemical and physical data
Formula	C28H32Cl2N4O6S2
Molar mass	655.61 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)C[C@H](NC(C1=CC2=CC=CC=C2S1)=O)C(N3CCN(CC3)C([C@H](CO)NS(=O)(C4=C(Cl)C=C(Cl)C=C4)=O)=O)=O
InChI InChI=1S/C28H32Cl2N4O6S2/c1-17(2)13-21(31-26(36)24-14-18-5-3-4-6-23(18)41-24)27(37)33-9-11-34(12-10-33)28(38)22(16-35)32-42(39,40)25-8-7-19(29)15-20(25)30/h3-8,14-15,17,21-22,32,35H,9-13,16H2,1-2H3,(H,31,36)/t21-,22-/m0/s1 Key:IVYQPSHHYIAUFO-VXKWHMMOSA-N

GSK1016790A (akaGSK101) is a drug developed byGlaxoSmithKline which acts as a potent and selectiveagonist for theTRPV4 receptor. It has been used to study the role of TRPV4 receptors in the function ofsmooth muscle tissue, particularly that lining blood vessels,lymphatic system, and thebladder.^{[1][2][3][4][5]}

Thispharmacology-related article is astub. You can help Wikipedia byexpanding it.

• v
• t
• e

• Piperazines
• Pharmacology stubs

• Articles with short description
• Short description matches Wikidata
• Short description is different from Wikidata
• Chemical pages without DrugBank identifier
• Articles without KEGG source
• Articles without UNII source
• Drugs missing an ATC code
• Drugs with no legal status
• Articles containing unverified chemical infoboxes
• All stub articles