As the gamma subunit (Gγ) of three different families of G proteins (G(I)/Gi, G(S)/Gs and G(O)Go), GNGT2 is expressed in at least 23tissues[8] and other cell types, includingmonocytes of the vertebrateinnate immune system, where at increased levels it has been shown to be a potentialprognostic marker for some types of cancer, includingesophageal cancer.[9]
Several transcript variants encoding the GNGT2 protein have been found for the GNGT2 gene. There is evidence for use of multiplepolyadenylation sites by this gene.[6]
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ong OC, Hu K, Rong H, Lee RH, Fung BK (Nov 1997). "Gene structure and chromosome localization of the G gamma c subunit of human cone G-protein (GNGT2)".Genomics.44 (1):101–9.doi:10.1006/geno.1997.4814.PMID9286705.
Huang CL, Jan YN, Jan LY (1997). "Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels".FEBS Lett.405 (3):291–8.doi:10.1016/S0014-5793(97)00197-X.PMID9108307.S2CID44072628.
