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GNA14

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
GNA14
Identifiers
AliasesGNA14, G protein subunit alpha 14, HG1I
External IDsOMIM:604397;MGI:95769;HomoloGene:68386;GeneCards:GNA14;OMA:GNA14 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for GNA14
Genomic location for GNA14
Band9q21.2Start77,423,079bp[1]
End77,648,322bp[1]
Gene location (Mouse)
Chromosome 19 (mouse)
Chr.Chromosome 19 (mouse)[2]
Chromosome 19 (mouse)
Genomic location for GNA14
Genomic location for GNA14
Band19 A|19 11.29 cMStart16,413,126bp[2]
End16,588,184bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • bronchial epithelial cell

  • testicle

  • C1 segment

  • smooth muscle tissue

  • left lobe of thyroid gland

  • tail of epididymis

  • olfactory zone of nasal mucosa

  • right lobe of thyroid gland

  • body of uterus
Top expressed in
  • lumbar spinal ganglion

  • vestibular membrane of cochlear duct

  • zygote

  • secondary oocyte

  • facial motor nucleus

  • primary oocyte

  • left colon

  • gastrula

  • right kidney

  • stria vascularis
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9630

14675

Ensembl

ENSG00000156049

ENSMUSG00000024697

UniProt

O95837

P30677

RefSeq (mRNA)

NM_004297

NM_008137

RefSeq (protein)

NP_004288

NP_032163

Location (UCSC)Chr 9: 77.42 – 77.65 MbChr 19: 16.41 – 16.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-14 is aprotein that in humans is encoded by theGNA14gene.[5][6][7] G14α is a member of theGq alpha subunit family, and functions as a constituent of aheterotrimeric G protein in cellsignal transduction.

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000156049Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000024697Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993)."Evolution of the mammalian G protein alpha subunit multigene family".Nat Genet.1 (2):85–91.doi:10.1038/ng0592-85.PMID 1302014.S2CID 31888533.
  6. ^"Entrez Gene: GNA14 G protein subunit alpha 14 [ Homo sapiens (human) ]". Retrieved2019-07-25.
  7. ^GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-14; GNA14 atOMIM. Retrieved JULY 25, 2019.
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