Gamma-aminobutyric acid receptor subunit rho-1 is aprotein that in humans is encoded by theGABRR1gene.[5][6][7]
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family.[7]
^Cutting GR, Curristin S,Zoghbi H, O'Hara B, Seldin MF, Uhl GR (May 1992). "Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4".Genomics.12 (4):801–806.doi:10.1016/0888-7543(92)90312-G.PMID1315307.
Kusama T, Hatama K, Sakurai M, et al. (1999). "Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation".Neurosci. Lett.255 (1):17–20.doi:10.1016/S0304-3940(98)00696-X.PMID9839716.S2CID12933301.
Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (1999). "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3".Biochim. Biophys. Acta.1447 (2–3):307–312.doi:10.1016/S0167-4781(99)00167-0.PMID10542332.
Filippova N, Sedelnikova A, Zong Y, et al. (2000). "Regulation of recombinant gamma-aminobutyric acid (GABA)(A) and GABA(C) receptors by protein kinase C".Mol. Pharmacol.57 (5):847–856.doi:10.1016/S0026-895X(24)26492-0.PMID10779366.
Wang QW, Li ZW, Wang F, Yang JQ (2002). "Modulation by divalent cations of GABA rho 1 receptor from human retina expressed in Xenopus oocytes".Biomed. Environ. Sci.14 (4):269–277.PMID11862606.
Martínez-Torres A, Miledi R (2004). "A single amino acid change within the ion-channel domain of the gamma-aminobutyric acid rho1 receptor accelerates desensitization and increases taurine agonism".Arch. Med. Res.35 (3):194–198.doi:10.1016/j.arcmed.2003.12.002.PMID15163459.
