Fuselloviridae
Virus classification
(unranked):	Virus
Family:	Fuselloviridae
Genera
Alphafusellovirus Betafusellovirus
Synonyms
Fuselloviridae ICTV 1993 SSV1-type phages ICTV 1991 SSV-1 family ICTV 1990

Fuselloviridae is a family ofviruses.Sulfolobus species, specifically shibatae, solfataricus, and islandicus, serve as natural hosts. There are two genera in the family.^[1][2] Viruses inFuselloviridae are ubiquitous in high-temperature (≥70 °C), acidic (pH ≤4)hot springs around the world.

The family contains the following genera:^[2]

• Alphafusellovirus
• Betafusellovirus

Viruses inFuselloviridae are enveloped, with lemon-shaped geometries. The diameter is around 60 nm, with a length of 100 nm. Genomes consist of double-stranded circular DNA, around 17.3 kb in length.^[1] Biochemical characterization of SSV1, a prototypical fusellovirus, showed that virions are composed of four virus-encoded structural proteins, VP1 to VP4, as well as one DNA-binding chromatin protein of cellular origin. The virion proteins VP1, VP3, and VP4 undergo posttranslational modification by glycosylation, seemingly at multiple sites. VP1 is also proteolytically processed. SSV1 virions contain glycerol dibiphytanyl glycerol tetraether (GDGT) lipids, which appear to be acquired by the virus in a selective manner from the host cytoplasmic membrane.^[4]

Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. DNA templated transcription is the method of transcription.Sulfolobus shibatae,S. solfataricus, andS. islandicus serve as the natural host.^[1] Fuselloviruses are released from the host without causing cell lysis by a budding mechanism, similar to that employed by enveloped eukaryotic viruses.^[3]

• Viralzone: Fuselloviridae
• ICTV

• Fuselloviridae
• Archaeal viruses
• Virus families

• Articles with short description
• Short description matches Wikidata
• Use dmy dates from April 2017
• Articles with 'species' microformats