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 | |
| Names | |
|---|---|
| IUPAC name 6-O-Phosphono-α-D-fructofuranose | |
| Other names β-D-fructose 6-phosphate, fructose 6-phosphate | |
| Identifiers | |
| |
3D model (JSmol) | |
| Abbreviations | F6P |
| ChEBI | |
| ChemSpider |
|
| ECHA InfoCard | 100.010.360 |
| KEGG | |
| UNII | |
| |
| |
| Properties | |
| C6H13O9P | |
| Molar mass | 260.14 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Fructose 6-phosphate (sometimes called theNeuberg ester) is a derivative offructose, which has beenphosphorylated at the 6-hydroxy group. It is one of several possiblefructosephosphates. The β-D-form of this compound is very common incells.[1][2] The great majority ofglucose is converted to fructose 6-phosphate upon entering a cell.Fructose is predominantly converted tofructose 1-phosphate byfructokinase following cellular import.
The nameNeuberg ester comes from the German biochemistCarl Neuberg. In 1918, he found that the compound (later identified as fructose 6-phosphate) was produced by mild acid hydrolysis offructose 2,6-bisphosphate.[3]
Fructose 6-phosphate lies within theglycolysismetabolic pathway and is produced by isomerisation ofglucose 6-phosphate. It is in turn further phosphorylated tofructose-1,6-bisphosphate.
| α-D-glucose 6-phosphate | Phosphoglucose isomerase | β-D-fructose 6-phosphate | Phosphofructokinase-1 | β-D-fructose 1,6-bisphosphate | ||
 | |  | ||||
| ATP | ADP | |||||
 |  | |||||
| Pi | H2O | |||||
| Phosphoglucose isomerase | Fructose bisphosphatase | |||||
CompoundC00668 atKEGG Pathway Database.Enzyme5.3.1.9 atKEGG Pathway Database.CompoundC05345 atKEGG Pathway Database.Enzyme2.7.1.11 atKEGG Pathway Database.Enzyme3.1.3.11 atKEGG Pathway Database.Reaction[1] atKEGG Pathway Database.CompoundC05378 atKEGG Pathway Database.
Click on genes, proteins and metabolites below to link to respective articles.[§ 1]
