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Fluprednidene

From Wikipedia, the free encyclopedia
Chemical compound
Not to be confused withFluprednidene acetate.
Pharmaceutical compound
Fluprednidene
Clinical data
Other namesFluprednylidene; 9α-Fluoro-11β,17α,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione
Drug classCorticosteroid;Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
ECHA InfoCard100.016.901Edit this at Wikidata
Chemical and physical data
FormulaC22H27FO5
Molar mass390.451 g·mol−1
3D model (JSmol)
  • C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC(=C)[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@@]43C)F)O
  • InChI=1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1
  • Key:YVHXHNGGPURVOS-SBTDHBFYSA-N

Fluprednidene, also known asfluprednylidene, is asyntheticglucocorticoidcorticosteroid which was never marketed.[1][2][3] Anacetateester of fluprednidene,fluprednidene acetate, in contrast, has been marketed.[1][2][3]

References

[edit]
  1. ^abElks J (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 570–.ISBN 978-1-4757-2085-3.
  2. ^abIndex Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 463–.ISBN 978-3-88763-075-1.
  3. ^abChallener CA (1 December 2001).Chiral Drugs. Wiley. p. 490.ISBN 978-0-566-08411-9.


GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others


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