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Fibrocartilage

From Wikipedia, the free encyclopedia
Type of tissue
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Fibrocartilage
White fibrocartilage from anintervertebral fibrocartilage.
Symphysis pubis exposed by acoronal section. (Pubic symphysis visible at center left.)
Identifiers
MeSHD051445
TA21541
THH2.00.03.5.00017
FMA64784
Anatomical terminology

Fibrocartilage consists of a mixture of white fibrous tissue and cartilaginous tissue in various proportions. It owes its inflexibility and toughness to the former of these constituents, and itselasticity to the latter. It is the only type ofcartilage that containstype I collagen in addition to the normaltype II.

Structure

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Theextracellular matrix of fibrocartilage is mainly made fromtype I collagen secreted bychondroblasts.[1]

Locations of fibrocartilage in the human body

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Function

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Repair

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Ifhyaline cartilage is torn all the way down to the bone, the blood supply from inside the bone is sometimes enough to start some healing inside the lesion. In cases like this, the body will form a scar in the area using a special type of cartilage called fibrocartilage.[2] Fibrocartilage is a tough, dense, and fibrous material that helps fill in the torn part of the cartilage; however, it is not an ideal replacement for the smooth, glassy articular cartilage that normally covers the surface of joints.[2]

Clinical significance

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Micrograph showing a fragment of anintervertebral disc demonstrating degenerative fibrocartilage with loss of nuclei and nests of chondrocytes, as seen indegenerative disc disease.HPS stain.

Degeneration of fibrocartilage is seen indegenerative disc disease.

See also

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References

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Public domainThis article incorporates text in thepublic domain frompage 281 of the 20th edition ofGray's Anatomy(1918)

  1. ^Maynard, Robert Lewis; Downes, Noel (2019-01-01), Maynard, Robert Lewis; Downes, Noel (eds.),"Chapter 3 - Introduction to the Skeleton: Bone, Cartilage and Joints",Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research, Academic Press, pp. 11–22,ISBN 978-0-12-811837-5, retrieved2021-01-04
  2. ^ab"Articular cartilage damage".londonkneeclinic.com. Retrieved2024-11-30.

External links

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Cartilage
Bone
Ossification
Cells
Matrix
Types
Regions
Structure
Shapes
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