 | |
| Names | |
|---|---|
| Systematic IUPAC name Iron; (2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanoic acid | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChemSpider |
|
| ECHA InfoCard | 100.131.978 |
| E number | E579(acidity regulators, ...) |
| UNII | |
| |
| |
| Properties | |
| FeC12H22O14 | |
| Molar mass | 446.14 g/mol |
| Appearance | light yellow to brown powder |
| Odor | slight caramel odor |
| Melting point | 188 °C (370 °F; 461 K) dihydrate |
| soluble | |
| Solubility | soluble inglycerin negligible inalcohol |
| Pharmacology | |
| B03AA03 (WHO) B03AD05 (WHO) (combination withfolic acid) | |
| Hazards | |
| Safety data sheet (SDS) | Oxford MSDS |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Iron(II) gluconate, orferrous gluconate,[1] is a black compound often used as an iron supplement. It is the iron(II) salt ofgluconic acid. It is marketed under brand names such asFergon,Ferralet andSimron.[2]
Ferrous gluconate is effectively used in the treatment ofhypochromic anemia. The use of this compound compared with otheriron preparations results in satisfactoryreticulocyte responses, a high percentage utilization of iron, and daily increase inhemoglobin that a normal level occurs in a reasonably short time.[3]
Ferrous gluconate is also used as afood additive when processing blackolives. It is represented by the food labelingE number E579 in Europe. It imparts a uniform jet black color to the olives.[4][5]
Ferrous gluconate may betoxic in case of overdose. Children may show signs of toxicity with ingestions of 10–20 mg/kg of elemental iron. Serious toxicity may result from ingestions of more than 60 mg/kg. Iron exerts both local and systemic effects: it is corrosive to the gastrointestinalmucosa, it can have a negative impact on the heart and blood (dehydration, lowblood pressure, fast and weak pulse,shock), lungs, liver, gastrointestinal system (diarrhea, nausea, vomiting blood), nervous system (chills, dizziness,coma, convulsions, headache), and skin (flushing, loss of color, bluish-colored lips and fingernails).[6][7] The symptoms may disappear in a few hours, but then emerge again after 1 or more days.[citation needed]
