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Routes of administration | Oral |
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Formula | C17H17Cl2NO |
Molar mass | 322.23 g·mol−1 |
Fengabine (SL-79,229) is adrug which was investigated as anantidepressant but was never marketed.[1][2] Itsmechanism of action is unknown, but its antidepressant effects are reversed byGABAA receptorantagonists likebicuculline and it has hence been labeled asGABAergic; however, it does not actuallybind toGABA receptors, nor does it inhibitGABA-T.[1][2] Inclinical trials, fengabine's efficacy was comparable to that of thetricyclic antidepressants, but with a more rapidonset of action and much lessside effects.[3][4][5] Notably, fengabine lacks anysedative effects.[4]