 | |
| Names | |
|---|---|
| IUPAC name 3-{3-[(2R,3S)-3-Hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | |
| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.208.679 |
| UNII | |
| |
| |
| Properties | |
| C16H19N3O3 | |
| Molar mass | 301.346 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Febrifugine is aquinazolinonealkaloid first isolated from the Chinese herbDichroa febrifuga, but also found in the garden plantHydrangea.[1] Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.[2]
Febrifugine hasantimalarial properties and the synthetichalogenatedderivativehalofuginone is used in veterinary medicine as acoccidiostat. Other synthetic febrifugine derivatives have been used against malaria, cancer, fibrosis, and inflammatory disease.[3]
