Fe,Fi,Fo,Fum, andPhooey were fivemice who traveled to theMoon and circled it 75 times on the 1972Apollo 17 mission. NASA gave them identification numbersA3305,A3326,A3352,A3356, andA3400, and their nicknames were given by the Apollo 17 crew (Eugene Cernan,Harrison Schmitt, andRonald Evans). The four male mice, one female mouse, and Evans orbited the Moon for a record-setting six days and four hours in theApollo command moduleAmerica as Cernan and Schmitt performed theApollo program's last lunar excursions.

The mice travelled in individual compartments of tubes inside an aluminium container with "a sufficient food supply, temperature control, and a reserve ofpotassium superoxide that absorbed the CO₂ from their respiration and provided them with fresh oxygen."^[1] One of the male mice died (A-3352^[2]) during the trip, and the four survivors were euthanized and dissected for their expected biological information upon their return from the Moon.^[3]

The threeastronauts and the five mice were the last Earthlings to travel to and orbit the Moon.^[4] Evans and the five mice share two living-beingspaceflight records, the longest amount of time spent in lunar orbit (147 hours 43 minutes), and the most lunar orbits completed (75).^[5]

Apollo 17 launched December 7, 1972, and returned to Earth on December 19. Abiological cosmic ray experiment (BIOCORE) carried the fivepocket mice (Perognathus longimembris), a species chosen for the experiment because they had well documented biological responses. Some advantages of the species included their small size, ease of maintenance in an isolated state (requiring no drinking water for the expected duration of the mission and producing highly concentrated waste), and their proven capability of withstanding environmental stress.

Fe, Fi, Fo, Fum, and Phooey had been implanted with radiation monitors under their scalps to see whether they would suffer damage from cosmic rays.^[6] Four of the five mice survived the flight; the cause of death of the fifth was not determined.^[6]

After their return to Earth, the four remaining live mice were euthanized and dissected. Althoughlesions in the scalp and liver were detected, they appeared to be unrelated to one another and were not thought to be the result of cosmic rays. No damage was found in the mice'sretinas orviscera.^[6] At the time of the publication of the Apollo 17 Preliminary Science Report the mice's brains had not yet been examined,^[6] but subsequent studies showed no significant effect on their brains.^[2]

• 
  The night launch of Apollo 17, December 7, 1972
• 
  The Apollo 17space capsule about to splash down in the south Pacific Ocean.
• 
  The mice and Command ModuleAmerica retrieved by theUSSTiconderoga, December 19, 1972 (the three astronauts were already on board the ship)
• 
  Apollo 17 mission insignia

• Animals in space
• Zond 5, aSoviet space programcircumlunar voyage in September 1968, by two tortoises and assorted small plants and insects. They were the first Earthlings to fly to the vicinity of the Moon.
• Zond 6, turtles on a circumlunar mission in November 1968
• Zond 7, four turtles flew the August 1969 circumlunar flight
• Fee-fi-fo-fum, the namesake portion of the 1734 English fairy tale "Jack and the Beanstalk"

• Space exchange, October, 2020
• Unilad article, April 28, 2021

• Apollo 17
• Animals in space
• Perognathus
• Individual animals in the United States
• Individual mice
• Cosmic-ray experiments
• Space science experiments
• Ronald Evans (astronaut)
• Animal testing in the United States
• Animal deaths by euthanasia
• 1972 in spaceflight
• 1972 animal deaths
• Quintets

• CS1: long volume value
• Articles with short description
• Short description matches Wikidata