Movatterモバイル変換

Jump to content

Fazadinium bromide

From Wikipedia, the free encyclopedia

(Redirected fromFazadinium)

Chemical compound

Pharmaceutical compound

Fazadinium bromide
Clinical data

Trade names	Fazadon
ATC code	M03AC08 (WHO)
Identifiers
IUPAC name (E)-bis(3-methyl-2-phenylimidazo[3,2-a] pyridin-4-ium-1-yl)diazene dibromide
CAS Number	49564-56-9^N
PubChemCID	6321422
ChemSpider	21161354^N
UNII	8WV5538LFK
KEGG	D07273^Y
CompTox Dashboard(EPA)	DTXSID4023040
ECHA InfoCard	100.051.236
Chemical and physical data
Formula	C₂₈H₂₄Br₂N₆
Molar mass	604.350 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Cc1c(n(c2[n+]1cccc2)N=Nn3c4cccc[n+]4c(c3c5ccccc5)C)c6ccccc6.[Br-].[Br-]
InChI InChI=1S/C28H24N6.2BrH/c1-21-27(23-13-5-3-6-14-23)33(25-17-9-11-19-31(21)25)29-30-34-26-18-10-12-20-32(26)22(2)28(34)24-15-7-4-8-16-24;;/h3-20H,1-2H3;2*1H/q+2;;/p-2^N Key:LBOZSXSPRGACHC-UHFFFAOYSA-L^N
^NY (what is this?) (verify)

Fazadinium bromide is amuscle relaxant which acts as anicotinic acetylcholine receptor antagonist throughneuromuscular blockade.^[1]

References

^Camu F, D'Hollander A (1978). "Neuromuscular blockade of fazadinium bromide (AH 8165) in renal failure patients".Acta Anaesthesiologica Scandinavica.22 (3):221–6.doi:10.1111/aas.1978.22.3.221.PMID 27936.

v
t
e

Skeletalmuscle relaxants (M03)

Peripherally acting
(primarilyantinicotinic,
NMJ block)

Non-depolarizing

Curare alkaloids	Alcuronium Dimethyltubocurarine Tubocurarine
4° ammonium agents	ultra-short duration:Gantacurium short duration:Rapacuronium Mivacurium Chandonium intermediate duration:Atracurium Cisatracurium Fazadinium Rocuronium Vecuronium long duration:Doxacurium Dimethyltubocurarine Pancuronium Pipecuronium Laudexium Gallamine unsorted:Hexafluronium (Hexafluorenium)

Choline derivatives:Suxamethonium (Succinylcholine)

Polyalkylene derivatives:Hexamethonium

ACh release inhibitors

Botulinum toxin

Centrally acting

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Phenprobamate Styramate Tybamate
Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam
Nonbenzodiazepines	Eszopiclone
Thienodiazepines	Etizolam
Quinazolines	Methaqualone
Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine
Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Eperisone Fenyramidol Flopropione Gabapentin GHB Inaperisone Lanperisone Mephenesin Mephenoxalone Metaxalone Methocarbamol Phenibut Pregabalin Pridinol Promoxolane Quinine Silperisone Thiocolchicoside Tizanidine Tolperisone Zoxazolamine

Directly acting

Dantrolene

v
t
e

Nicotinic acetylcholine receptor modulators

nAChRsTooltip Nicotinic acetylcholine receptors

Agonists
(and PAMsTooltip positive allosteric modulators)

Antagonists
(and NAMsTooltip negative allosteric modulators)

Precursors
(andprodrugs)

See also: Receptor/signaling modulators; Muscarinic acetylcholine receptor modulators; Acetylcholine metabolism/transport modulators

Thisdrug article relating to themusculoskeletal system is astub. You can help Wikipedia byexpanding it.

v
t
e

Retrieved from "https://en.wikipedia.org/w/index.php?title=Fazadinium_bromide&oldid=1135223387"

Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp