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FTSJ3

From Wikipedia, the free encyclopedia
Class of enzymes
FTSJ3
Identifiers
AliasesFTSJ3, EPCS3, SPB1, FtsJ homolog 3, FtsJ RNA methyltransferase homolog 3, FtsJ RNA 2'-O-methyltransferase 3
External IDsOMIM:618411;MGI:1860295;HomoloGene:5451;GeneCards:FTSJ3;OMA:FTSJ3 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for FTSJ3
Genomic location for FTSJ3
Band17q23.3Start63,819,433bp[1]
End63,830,012bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for FTSJ3
Genomic location for FTSJ3
Band11 E1|11 68.89 cMStart106,139,968bp[2]
End106,146,905bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • sural nerve

  • tendon of biceps brachii

  • stromal cell of endometrium

  • gastric mucosa

  • right ovary

  • right adrenal gland

  • right lobe of thyroid gland

  • body of uterus

  • canal of the cervix
Top expressed in
  • tail of embryo

  • genital tubercle

  • epiblast

  • ventricular zone

  • yolk sac

  • blastocyst

  • embryo

  • zygote

  • morula

  • morula
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

117246

56095

Ensembl

ENSG00000108592

ENSMUSG00000020706

UniProt

Q8IY81

Q9DBE9

RefSeq (mRNA)

NM_017647

NM_025310

RefSeq (protein)

NP_060117

NP_079586

Location (UCSC)Chr 17: 63.82 – 63.83 MbChr 11: 106.14 – 106.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 is anenzyme, anO-methyltransferase, that in humans is encoded by theFTSJ3gene.[5]

Function

[edit]

The enzyme performs2′-O-methylation of RNA usingS-adenosylmethionine asmethyl donor.

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000108592 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000020706 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"FTSJ3 FtsJ RNA 2'-O-methyltransferase 3 [ Homo sapiens (human) ]". Retrieved8 August 2024.

Further reading

[edit]


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