| Clinical data | |
|---|---|
| Trade names | Duranest |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a603026 |
| Pregnancy category |
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| Routes of administration | Parenteral |
| ATC code | |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | n/a |
| Metabolism | Hepatic |
| Eliminationhalf-life | 2.5 hours |
| Excretion | Renal |
| Identifiers | |
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| CAS Number | |
| PubChemCID | |
| IUPHAR/BPS | |
| DrugBank |
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| ChemSpider |
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| UNII | |
| KEGG |
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| ChEBI | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.048.296 |
| Chemical and physical data | |
| Formula | C17H28N2O |
| Molar mass | 276.424 g·mol−1 |
| 3D model (JSmol) | |
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Etidocaine, marketed under the trade nameDuranest, is an amide-typelocal anesthetic given byinjection duringsurgical procedures andlabor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of use during dentistry is increased bleeding during surgery.[1]

The amide reaction between2,6-xylidine (1) and 2-bromobutyryl chloride [22118-12-3] (2) gives 2-Bromo-N-(2,6-Dimethylphenyl)Butanamide [53984-81-9] (3). Alkylation with N-Ethylpropylamine [20193-20-8] (4) givesEtidocaine (5).
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