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| Other names | 17α-Ethyltestosterone; 17α-Ethylandrost-4-en-17β-ol-3-one; 17α-Pregn-4-en-17-ol-3-one |
| Routes of administration | By mouth |
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| Chemical and physical data | |
| Formula | C21H32O2 |
| Molar mass | 316.485 g·mol−1 |
| 3D model (JSmol) | |
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Ethyltestosterone, or17α-ethyltestosterone, also known as17α-ethylandrost-4-en-17β-ol-3-one or17α-pregn-4-en-17-ol-3-one, is asynthetic,orally activeanabolic–androgenic steroid (AAS) of the17α-alkylated group related tomethyltestosterone which was never marketed.[1][2] Like methyltestosterone, ethyltestosterone is theparent compound of many AAS.[3] Derivatives of ethyltestosterone includenorethandrolone (ethylnandrolone, ethylestrenolone),ethylestrenol (ethylnandrol),norboletone,ethyldienolone,tetrahydrogestrinone,bolenol (ethylnorandrostenol), andpropetandrol.[3]
Ethyltestosterone is described as a very weak AAS[4][5] and is considerably weaker as an AAS than is methyltestosterone.[6] It is reported to have 1/10 of theanabolicpotency and 1/20 of theandrogenic potency oftestosterone propionate in rodents.[7] Ethyltestosterone was also inactive in boys withdwarfism at 20 to 40 mg/dayorally.[7] The low potency of ethyltestosterone is in notable contrast tonorethandrolone (17α-ethyl-19-nortestosterone), the C19 nor analogue.[4]Analogues of ethyltestosterone with longer C17αchains such aspropyltestosterone (topterone) have further reduced androgenic activity or evenantiandrogenic activity.[2][8] In contrast to ethyltestosterone, its 19-demethyl variant, norethandrolone, is a potent AAS comparable inanabolic activity totestosterone propionate.[5]
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