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Ethenzamide

From Wikipedia, the free encyclopedia
NSAID analgesic drug
Pharmaceutical compound
Ethenzamide
Clinical data
ATC code
Identifiers
  • 2-ethoxybenzamide
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.012.133Edit this at Wikidata
Chemical and physical data
FormulaC9H11NO2
Molar mass165.192 g·mol−1
3D model (JSmol)
  • O=C(c1ccccc1OCC)N
  • InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11) checkY
  • Key:SBNKFTQSBPKMBZ-UHFFFAOYSA-N checkY
  (verify)

Ethenzamide (2-ethoxybenzamide) is a commonanalgesic andanti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.[1][2] It is also an ingredient in numerouscold medications and many prescription analgesics.[citation needed] It is used as anover-the-counter drug inJapan, often in combination withcaffeine andacetaminophen, where it is marketed for uses including toothache, menstrual cramps, headache, and fever.[3]

It is metabolizedin vivo intosalicylamide.[4]

References

[edit]
  1. ^Darias V, Bravo L, Abdallah SS, Sánchez Mateo CC, Expósito-Orta MA, Lissavetsky J, Manzanares J (February 1992). "Synthesis and preliminary pharmacological study of thiophene analogues of the antipyretic and analgesic agent ethenzamide".Archiv der Pharmazie.325 (2):83–7.doi:10.1002/ardp.19923250206.PMID 1605721.S2CID 28098596.
  2. ^Wang PJ, Guo HR (2004)."Frequent analgesics consumption in migraineurs: Comparison between chronic and episodic migraineurs".The Journal of Headache and Pain.5 (1):30–35.doi:10.1007/s10194-004-0065-x.PMC 3452147.
  3. ^"OTC Pain Relief Medicine in Japan".Life Abroad. RetrievedMarch 22, 2021.
  4. ^"エテンザミド" [Ethenzamide] (in Japanese). RetrievedMarch 22, 2021.
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;withdrawn drugs;veterinary use.
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(
PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


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Retrieved from "https://en.wikipedia.org/w/index.php?title=Ethenzamide&oldid=1268661660"
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