| Clinical data | |
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| Trade names | Analepticon |
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| ECHA InfoCard | 100.005.599 |
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| Formula | C12H17NO3 |
| Molar mass | 223.272 g·mol−1 |
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Etamivan (INN, orethamivan (USAN); trade namesAnalepticon,Emivan, andVandid) is arespiratory stimulant drug[1] related tonikethamide. It was mainly used in the treatment ofbarbiturateoverdose[2] andchronic obstructive pulmonary disease,[3] but has now largely fallen into disuse.
Adverse effects which are common to the respiratory stimulant class include sneezing, coughing, andlaryngospasm when infused too rapidly. More serious adverse events include muscle twitching, tremors, and convulsions. The dose to treat barbiturate intoxication orcarbon dioxide narcosis in adults ranges from 0.5 mg/kg to 5.0 mg/kg, infused intravenously over several minutes. Epilepsy and the use ofmonoamine oxidase inhibitors or otheradrenergic drugs are contraindications.[4]
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