End-systolic volume (ESV) is the volume of blood in aventricle at the end of contraction, orsystole, and the beginning of filling, ordiastole.
ESV is the lowest volume of blood in the ventricle at any point in thecardiac cycle.The main factors that affect the end-systolic volume areafterload and thecontractility of the heart.
End systolic volume can be used clinically as a measurement of the adequacy of cardiac emptying, related to systolic function. On anelectrocardiogram, orECG, the end-systolic volume will be seen at the end of the T wave. Clinically, ESV can be measured using two-dimensionalechocardiography, MRI (magnetic resonance tomography) or cardiac CT (computed tomography) or SPECT (single photon emission computed tomography).[citation needed]
Along withend-diastolic volume, ESV determines the stroke volume, or output of blood by the heart during a single phase of the cardiac cycle.[1] Thestroke volume is the difference between theend-diastolic volume and the end-systolic volume. The end-systolic values in the table below are for the left ventricle:[citation needed]
| Ventricular volumes | ||
|---|---|---|
| Measure | Right ventricle | Left ventricle |
| End-diastolic volume | 144 mL (± 23 mL)[2] | 142 mL (± 21 mL)[3] |
| End-diastolic volume / body surface area (mL/m2) | 78 mL/m2 (± 11 mL/m2)[2] | 78 mL/m2 (± 8.8 mL/m2)[3] |
| End-systolic volume | 50 mL (± 14 mL)[2] | 47 mL (± 10 mL)[3] |
| End-systolic volume / body surface area (mL/m2) | 27 mL/m2 (± 7 mL/m2)[2] | 26 mL/m2 (± 5.1 mL/m2)[3] |
| Stroke volume | 94 mL (± 15 mL)[2] | 95 mL (± 14 mL)[3] |
| Stroke volume / body surface area (mL/m2) | 51 mL/m2 (± 7 mL/m2)[2] | 52 mL/m2 (± 6.2 mL/m2)[3] |
| Ejection fraction | 66% (± 6%)[2] | 67% (± 4.6%)[3] |
| Heart rate | 60–100bpm[4] | 60–100bpm[4] |
| Cardiac output | 4.0–8.0L/minute[5] | 4.0–8.0L/minute[5] |
The right ventricular end-systolic volume (RVESV) normally ranges between 50 and 100 mL.[5]
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