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| Names | |
|---|---|
| IUPAC name 2-isopropyl-5-(methyl- (2-phenylethyl)amino)- 2-phenylpentanenitrile | |
| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
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| Properties | |
| C23H30N2 | |
| Molar mass | 334.50 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Emopamil is acalcium channel blocker and a high-affinityligand of humansterolisomerase.[1]
Emopamil's structure consists of an organicamino compound,nitrile compound and a member of twobenzene rings.
Emopamil also known as EMP is aphenylalkylamine and inhibitor of5-hydroxytryptamine 5-HT2 receptors.[2] EMP includes a chiral quaternary carbon center, and research has indicated that itsoptical isomers have different biological effects.[3] It interacts in an extracellular site of thenerve cell to inhibit calcium channel responses while other phenylalkylamines act at an intracellular site. The interaction site of emopamil suggests to its greater neuroprotective efficacy in research related toischaemia.[4]
